ASB10 and MRPL23

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ASB10	MRPL23
Gene Name		ankyrin repeat and SOCS box containing 10	mitochondrial ribosomal protein L23
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleolus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit
	Molecular Function		Nucleotide Binding RNA Binding Structural Constituent Of Ribosome
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction	Translation Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS			DNA methylation (variation) ( 23725790)
Protein-Protein Interactions		4 interactors: AGR3 ARFGAP1 KDM1A MRPL23	4 interactors: ASB10 NDUFAB1 PNMA1 SPP1
Entrez ID		136371	6150
HPRD ID		10666	02876
Ensembl ID		ENSG00000146926	ENSG00000214026
Uniprot IDs		Q8WXI3	A8MYK1 Q16540
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Positive Regulation Of Megakaryocyte Differentiation COPI Coating Of Golgi Vesicle Positive Regulation Of Hormone Biosynthetic Process COPI-coated Vesicle Budding Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Golgi Vesicle Budding Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Vesicle Targeting, To, From Or Within Golgi Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Histone Demethylation Regulation Of Erythrocyte Differentiation Retrograde Vesicle-mediated Transport, Golgi To ER Protein Demethylation Localization Within Membrane Vesicle Targeting Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of DNA Binding Organelle Organization Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Regulation Of Histone Methylation Positive Regulation Of Nuclease Activity Positive Regulation Of Neural Precursor Cell Proliferation Pituitary Gland Development Negative Regulation Of Protein Binding	Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Protein Lipoylation Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Inflammatory Response Positive Regulation Of Bone Resorption Regulation Of Axon Regeneration
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