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LIMS2 and HIPK3
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
LIMS2
HIPK3
Gene Name
LIM and senescent cell antigen-like domains 2
homeodomain interacting protein kinase 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Plasma Membrane
Focal Adhesion
Nucleus
Cytoplasm
PML Body
Molecular Function
Zinc Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
ATP Binding
Biological Process
Single Organismal Cell-cell Adhesion
Cell Junction Assembly
Negative Regulation Of Apoptotic Process
Cell-cell Junction Organization
Negative Regulation Of Neural Precursor Cell Proliferation
Negative Regulation Of Hepatocyte Proliferation
Positive Regulation Of Integrin-mediated Signaling Pathway
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Apoptotic Process
MRNA Transcription
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Negative Regulation Of Apoptotic Process
Negative Regulation Of JUN Kinase Activity
Pathways
Cell junction organization
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Alzheimer's disease (cognitive decline) (
23535033
)
Protein-Protein Interactions
13 interactors:
APP
CALCOCO2
GOLGA2
HIPK3
ILK
KRT40
KRTAP10-3
KRTAP10-5
KRTAP10-7
MDFI
MTUS2
NOTCH2NL
RCHY1
36 interactors:
AR
ARRB2
C1QA
CREB1
DAXX
FADD
FAS
FLNC
GLUL
GORASP1
GRB2
HEYL
HNRNPA1
HNRNPA2B1
HNRNPH1
LIMD1
LIMK2
LIMS2
MBD1
MTMR4
NR2F2
RGS3
SIAH1
SIAH2
SKIL
SNIP1
SRSF1
SRSF5
SUMO1
TGFB1I1
TOX4
TP73
TRA2B
UBE2I
ZNF107
ZYX
Entrez ID
55679
10114
HPRD ID
06389
05111
Ensembl ID
ENSG00000072163
ENSG00000110422
Uniprot IDs
B3KNZ3
Q7Z4I7
Q9H422
PDB IDs
3IXE
Enriched GO Terms of Interacting Partners
?
Regulation Of Protein Kinase Activity
Regulation Of Binding
Regulation Of Kinase Activity
Regulation Of MAP Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of JUN Kinase Activity
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Binding
Regulation Of Phosphorylation
Synaptic Growth At Neuromuscular Junction
Peptidyl-serine Phosphorylation
Regulation Of Phosphorus Metabolic Process
Regulation Of MAPK Cascade
Notch Signaling Pathway
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Binding
Regulation Of JNK Cascade
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Catalytic Activity
Platelet Activation
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Cellular Protein Metabolic Process
Phosphorylation
Positive Regulation Of MAP Kinase Activity
Negative Regulation Of Protein Kinase Activity
Axon Choice Point Recognition
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Kinase Activity
Positive Regulation Of Protein Modification Process
Neuron Remodeling
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of JUN Kinase Activity
Regulation Of Developmental Growth
Positive Regulation Of Proteolysis
Negative Regulation Of Transferase Activity
Regulation Of Wnt Signaling Pathway
Fibroblast Migration
Extracellular Fibril Organization
Negative Regulation Of Protein Phosphorylation
Regulation Of Catalytic Activity
MRNA Transcription
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Negative Regulation Of Smooth Muscle Cell Migration
Regulation Of Signaling
Regulation Of Signal Transduction
Regulation Of RNA Metabolic Process
RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Gene Expression
Regulation Of Metabolic Process
Regulation Of Gene Expression
Regulation Of Cellular Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Component Assembly
Negative Regulation Of Gene Expression
Negative Regulation Of Signal Transduction
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Signaling
Negative Regulation Of Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Positive Regulation Of Signal Transduction
Regulation Of Transcription, DNA-templated
Heterocycle Metabolic Process
Motor Neuron Apoptotic Process
Transcription, DNA-templated
Cellular Aromatic Compound Metabolic Process
Protein Oligomerization
RNA Biosynthetic Process
Response To Organic Substance
Cellular Response To Organic Substance
RNA Splicing
Regulation Of Extrinsic Apoptotic Signaling Pathway
Viral Process
Regulation Of RNA Splicing
Cellular Metabolic Process
RNA Processing
Cellular Response To Growth Factor Stimulus
Androgen Receptor Signaling Pathway
Response To Growth Factor
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Signaling
Necroptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Tagcloud
?
al7a1
arhgap1
c25h16orf71
conceptus
ddx58
degs
endometria
ensbtat00000050193
estrus
f2rl2
fbxl7
herc6
ifi16
ifnt
insemination
loc507810
mgc127874
mgc128929
parp12
rnaseq
rnf213
samd9
serbp1
srgap2
tbc1d1
wbscr17
znfx1
zswim4
zxfx1
Tagcloud (Difference)
?
al7a1
arhgap1
c25h16orf71
conceptus
ddx58
degs
endometria
ensbtat00000050193
estrus
f2rl2
fbxl7
herc6
ifi16
ifnt
insemination
loc507810
mgc127874
mgc128929
parp12
rnaseq
rnf213
samd9
serbp1
srgap2
tbc1d1
wbscr17
znfx1
zswim4
zxfx1
Tagcloud (Intersection)
?