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LIMS2
Gene Name
LIM and senescent cell antigen-like domains 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Plasma Membrane
Focal Adhesion
Molecular Function
Zinc Ion Binding
Biological Process
Single Organismal Cell-cell Adhesion
Cell Junction Assembly
Negative Regulation Of Apoptotic Process
Cell-cell Junction Organization
Negative Regulation Of Neural Precursor Cell Proliferation
Negative Regulation Of Hepatocyte Proliferation
Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways
Cell junction organization
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Alzheimer's disease (cognitive decline) (
23535033
)
Protein-protein Interactions
13 interactors:
APP
CALCOCO2
GOLGA2
HIPK3
ILK
KRT40
KRTAP10-3
KRTAP10-5
KRTAP10-7
MDFI
MTUS2
NOTCH2NL
RCHY1
Entrez ID
55679
HPRD ID
06389
Ensembl ID
ENSG00000072163
Uniprot IDs
B3KNZ3
Q7Z4I7
PDB IDs
3IXE
Enriched GO Terms of Interacting Partners
?
Regulation Of Protein Kinase Activity
Regulation Of Binding
Regulation Of Kinase Activity
Regulation Of MAP Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of JUN Kinase Activity
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Binding
Regulation Of Phosphorylation
Synaptic Growth At Neuromuscular Junction
Peptidyl-serine Phosphorylation
Regulation Of Phosphorus Metabolic Process
Regulation Of MAPK Cascade
Notch Signaling Pathway
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Binding
Regulation Of JNK Cascade
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Catalytic Activity
Platelet Activation
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Cellular Protein Metabolic Process
Phosphorylation
Positive Regulation Of MAP Kinase Activity
Negative Regulation Of Protein Kinase Activity
Axon Choice Point Recognition
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Kinase Activity
Positive Regulation Of Protein Modification Process
Neuron Remodeling
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of JUN Kinase Activity
Regulation Of Developmental Growth
Positive Regulation Of Proteolysis
Negative Regulation Of Transferase Activity
Regulation Of Wnt Signaling Pathway
Fibroblast Migration
Extracellular Fibril Organization
Negative Regulation Of Protein Phosphorylation
Regulation Of Catalytic Activity
MRNA Transcription
Negative Regulation Of Striated Muscle Cell Apoptotic Process
Negative Regulation Of Smooth Muscle Cell Migration
Tagcloud
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al7a1
arhgap1
c25h16orf71
conceptus
ddx58
degs
endometria
ensbtat00000050193
estrus
f2rl2
fbxl7
herc6
ifi16
ifnt
insemination
loc507810
mgc127874
mgc128929
parp12
rnaseq
rnf213
samd9
serbp1
srgap2
tbc1d1
wbscr17
znfx1
zswim4
zxfx1