LIMS2 and KRTAP10-5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LIMS2	KRTAP10-5
Gene Name		LIM and senescent cell antigen-like domains 2	keratin associated protein 10-5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Focal Adhesion	Keratin Filament
	Molecular Function	Zinc Ion Binding
	Biological Process	Single Organismal Cell-cell Adhesion Cell Junction Assembly Negative Regulation Of Apoptotic Process Cell-cell Junction Organization Negative Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Hepatocyte Proliferation Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Cell junction organization Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033)
Protein-Protein Interactions		13 interactors: APP CALCOCO2 GOLGA2 HIPK3 ILK KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 MDFI MTUS2 NOTCH2NL RCHY1	108 interactors: ADAMTSL4 AEN ALDH3B1 AMOTL2 BCL6B BMP7 BYSL C11orf87 C19orf66 C9orf9 CARD9 CHRD CNNM3 CREB5 DHX57 ECE1 EIF4E2 ENKD1 FAM74A4 FAM76B FARS2 GATA1 GLIDR GLRX3 GNE GOLGA8EP HHEX HOXA1 HPCAL1 KRTAP10-3 KRTAP10-7 KRTAP12-1 KRTAP12-2 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LIMS2 LUZP4 MEOX2 MOBP MT1DP MXI1 NAA10 NOTCH2NL NPDC1 NR4A1 NUFIP2 OTX1 POM121L8P PRKAB2 PRR13 PVRL2 SCNM1 SLC23A1 SLC6A20 SMCP SPATA3 SPRY1 SPRY2 STK16 TBC1D16 THAP10 TNP2 TNS2 TRPV6 TULP3 TXNDC5 TYMSOS UTP23 WDYHV1 WT1-AS ZBTB24 ZBTB48 ZFYVE21 ZNF20 ZNF264 ZNF273 ZNF286A ZNF32 ZNF320 ZNF329 ZNF34 ZNF417 ZNF433 ZNF439 ZNF559 ZNF572 ZNF587 ZNF670 ZNF679 ZNF697 ZNF707 ZNF785 ZNF792 ZSCAN21 ZSCAN26
Entrez ID		55679	386680
HPRD ID		06389	11191
Ensembl ID		ENSG00000072163
Uniprot IDs		B3KNZ3 Q7Z4I7	P60370
PDB IDs		3IXE
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Kinase Activity Regulation Of Binding Regulation Of Kinase Activity Regulation Of MAP Kinase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of JUN Kinase Activity Positive Regulation Of Protein Metabolic Process Negative Regulation Of Binding Regulation Of Phosphorylation Synaptic Growth At Neuromuscular Junction Peptidyl-serine Phosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of MAPK Cascade Notch Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Regulation Of JNK Cascade Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Catalytic Activity Platelet Activation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cellular Protein Metabolic Process Phosphorylation Positive Regulation Of MAP Kinase Activity Negative Regulation Of Protein Kinase Activity Axon Choice Point Recognition Negative Regulation Of Protein Metabolic Process Negative Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Neuron Remodeling Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of JUN Kinase Activity Regulation Of Developmental Growth Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Fibroblast Migration Extracellular Fibril Organization Negative Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity MRNA Transcription Negative Regulation Of Striated Muscle Cell Apoptotic Process Negative Regulation Of Smooth Muscle Cell Migration	Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Biosynthetic Process Keratinization Regulation Of Nitrogen Compound Metabolic Process Keratinocyte Differentiation Regulation Of Metabolic Process Epidermal Cell Differentiation Epithelium Development Epidermis Development Cellular Process Cellular Metabolic Process Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Skin Development Tissue Development Regulation Of Cellular Process Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Organ Development Regulation Of Neurotrophin TRK Receptor Signaling Pathway Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Embryonic Neurocranium Morphogenesis Penetration Of Zona Pellucida Embryo Development Epithelial Cell Differentiation Epithelial Tube Branching Involved In Lung Morphogenesis Bud Elongation Involved In Lung Branching Pattern Specification Process Embryonic Organ Development Negative Regulation Of Protein Serine/threonine Kinase Activity Embryonic Morphogenesis Lung Morphogenesis Anterior/posterior Pattern Specification Respiratory Tube Development Negative Regulation Of Ras GTPase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		al7a1 arhgap1 c25h16orf71 conceptus ddx58 degs endometria ensbtat00000050193 estrus f2rl2 fbxl7 herc6 ifi16 ifnt insemination loc507810 mgc127874 mgc128929 parp12 rnaseq rnf213 samd9 serbp1 srgap2 tbc1d1 wbscr17 znfx1 zswim4 zxfx1
Tagcloud (Difference) ?		al7a1 arhgap1 c25h16orf71 conceptus ddx58 degs endometria ensbtat00000050193 estrus f2rl2 fbxl7 herc6 ifi16 ifnt insemination loc507810 mgc127874 mgc128929 parp12 rnaseq rnf213 samd9 serbp1 srgap2 tbc1d1 wbscr17 znfx1 zswim4 zxfx1
Tagcloud (Intersection) ?