ANKRD1

Gene Name		ankyrin repeat domain 1 (cardiac muscle)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Cytosol Sarcomere I Band
	Molecular Function	RNA Polymerase II Transcription Factor Binding RNA Polymerase II Transcription Coactivator Activity P53 Binding DNA Binding Transcription Corepressor Activity Protein Binding Titin Binding Histone Deacetylase Binding R-SMAD Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Neuron Projection Development Cellular Response To Drug Skeletal Muscle Cell Differentiation Response To Muscle Stretch Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Lipid Metabolic Process Small Molecule Metabolic Process Sarcomere Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Secretion Cardiac Muscle Tissue Morphogenesis Cellular Response To Lipopolysaccharide Cellular Response To Mechanical Stimulus Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Organic Cyclic Compound Cellular Response To Hypoxia Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of DNA Biosynthetic Process
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: CASQ2 MYPN TRIM55 TRIM63 TTN
Entrez ID		27063
HPRD ID		10647
Ensembl ID		ENSG00000148677
Uniprot IDs		Q15327
PDB IDs
Enriched GO Terms of Interacting Partners?		Sarcomere Organization Myofibril Assembly Actomyosin Structure Organization Striated Muscle Cell Development Muscle Cell Development Muscle Contraction Striated Muscle Cell Differentiation Muscle System Process Muscle Cell Differentiation Cardiac Muscle Contraction Heart Contraction Organelle Assembly Muscle Structure Development Striated Muscle Contraction Actin Cytoskeleton Organization Actin Filament-based Process Response To Calcium Ion Sarcomerogenesis Detection Of Muscle Stretch Skeletal Muscle Myosin Thick Filament Assembly Purkinje Myocyte To Ventricular Cardiac Muscle Cell Signaling Directional Locomotion Sequestering Of Calcium Ion Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Anatomical Structure Formation Involved In Morphogenesis Myosin Filament Assembly Cytoskeleton Organization Skeletal Muscle Atrophy Skeletal Muscle Thin Filament Assembly Striated Muscle Atrophy Muscle Atrophy Blood Circulation Cardiac Muscle Fiber Development Response To Muscle Stretch Skeletal Myofibril Assembly Response To Metal Ion Skeletal Muscle Adaptation Cellular Protein Complex Assembly Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sequestering Of Metal Ion Cellular Response To Caffeine Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Cellular Response To Organic Cyclic Compound Negative Regulation Of Potassium Ion Transmembrane Transport Cell-cell Signaling Involved In Cardiac Conduction Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Adult Heart Development
Tagcloud ?		adenovirus ang angiotensin ankyrin antagonized attempted cardiomyocyte cardiomyocytes carp constriction exacerbated exacerbates failing fractional hearts inconclusive infarction modulates myocardial nrcs overload permeability repeat shortening tac termed transverse upregulate upregulation