TRPV6 and PDE9A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRPV6	PDE9A
Gene Name		transient receptor potential cation channel, subfamily V, member 6	phosphodiesterase 9A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Endoplasmic Reticulum Golgi Apparatus Cytosol Ruffle Membrane Perikaryon Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Channel Activity Protein Binding Calmodulin Binding	3',5'-cyclic-nucleotide Phosphodiesterase Activity Protein Binding Metal Ion Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Calcium Ion Transport Regulation Of Calcium Ion-dependent Exocytosis Ion Transmembrane Transport Transmembrane Transport Calcium Ion Transmembrane Transport	Signal Transduction Blood Coagulation Metabolic Process CGMP-mediated Signaling
Pathways		Ion channel transport TRP channels Stimuli-sensing channels	Platelet homeostasis Nitric oxide stimulates guanylate cyclase cGMP effects
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: CALB1 CALM1 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-8 MDFI MID2 NEDD4 NOTCH2NL PDE9A PNMA1 PRKCA PTPN1 S100A10 TRAF1	18 interactors: BAG3 C9orf106 CLK1 CRY2 GORASP2 KRTAP10-3 KRTAP10-8 KRTAP4-2 KRTAP9-2 LAGE3 LMO2 NAA38 NOTCH2NL PHYHIPL SULT1E1 TRIM32 TRPV6 UTP23
Entrez ID		55503	5152
HPRD ID		05982	09115
Ensembl ID		ENSG00000165125	ENSG00000160191
Uniprot IDs		Q9H1D0	O76083
PDB IDs			2HD1 2YY2 3DY8 3DYL 3DYN 3DYQ 3DYS 3JSI 3JSW 3K3E 3K3H 3N3Z 3QI3 3QI4 4E90 4G2J 4G2L 4GH6
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Regulation Of Signal Transduction Cellular Response To Light Stimulus Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response Negative Regulation Of Transport Cellular Response To Radiation Blood Coagulation Hemostasis Response To Stress Response To Stimulus Regulation Of Rhodopsin Mediated Signaling Pathway Activation Of Adenylate Cyclase Activity Regulation Of Intracellular Signal Transduction Rhodopsin Mediated Signaling Pathway Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Platelet Activation Positive Regulation Of Adenylate Cyclase Activity Regulation Of Body Fluid Levels Wound Healing Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Lyase Activity Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Cell Activation Activation Of Phospholipase C Activity Response To Wounding Defense Response Immune System Process Regulation Of Adenylate Cyclase Activity Regulation Of Protein Kinase Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of CAMP Biosynthetic Process Negative Regulation Of Protein Phosphorylation Regulation Of Insulin Receptor Signaling Pathway Regulation Of Kinase Activity Regulation Of Cyclase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of CAMP Metabolic Process Innate Immune Response Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Metanephric Connecting Tubule Development Positive Regulation Of Dense Core Granule Biogenesis Transmission Of Virus Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity Development Involved In Symbiotic Interaction Response To Light Stimulus Positive Regulation Of Phospholipase Activity Phototransduction, Visible Light Regulation Of Cellular Response To Insulin Stimulus
Tagcloud ?		abca1 adamtsl3 aiming apc crc elac1 epha3 ephb6 ercc6 excluding exome fbxw7 germline kbiosciences marginal mll3 obscn pkhd1 recessive rs4987622 rs6464211 rs6947538 silico smad4 snps somatic spite strongest syne1	acetylcholinesterase adas aes cgi cgmp cog cognition diarrhea discontinuation elevates guanoscine impression memantine mini mmse monophosphate nausea neuropsychiatric npi overexpress pf pharmacokinetics phosphodiesterase placebo probable q12h subscale tg2576
Tagcloud (Difference) ?		abca1 adamtsl3 aiming apc crc elac1 epha3 ephb6 ercc6 excluding exome fbxw7 germline kbiosciences marginal mll3 obscn pkhd1 recessive rs4987622 rs6464211 rs6947538 silico smad4 snps somatic spite strongest syne1	acetylcholinesterase adas aes cgi cgmp cog cognition diarrhea discontinuation elevates guanoscine impression memantine mini mmse monophosphate nausea neuropsychiatric npi overexpress pf pharmacokinetics phosphodiesterase placebo probable q12h subscale tg2576
Tagcloud (Intersection) ?