TRPV6 and CALB1

Number of citations of the paper that reports this interaction (PubMedID 16763551)
48

Data Source:
HPRD (in vitro)

		TRPV6	CALB1
Description		transient receptor potential cation channel subfamily V member 6	calbindin 1
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GO Annotations	Cellular Component	Plasma Membrane Membrane Calcium Channel Complex	Nucleus Cytoplasm Cytosol Axon Dendrite Stereocilium Cuticular Plate Neuron Projection Neuronal Cell Body Terminal Bouton Calyx Of Held Synapse Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse Postsynapse Glutamatergic Synapse GABA-ergic Synapse Presynaptic Cytosol Postsynaptic Cytosol
	Molecular Function	Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding Identical Protein Binding Metal Ion Binding	Vitamin D Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Metal Ion Binding Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Regulation Of Calcium Ion-dependent Exocytosis Monoatomic Ion Transmembrane Transport Parathyroid Hormone Secretion Response To Calcium Ion Calcium Ion Homeostasis Transmembrane Transport Calcium Ion Transmembrane Transport Calcium Ion Import Across Plasma Membrane	Learning Or Memory Short-term Memory Long-term Memory Locomotory Behavior Retina Layer Formation Response To Auditory Stimulus Metanephric Part Of Ureteric Bud Development Regulation Of Synaptic Plasticity Calcium Ion Homeostasis Retina Development In Camera-type Eye Metanephric Collecting Duct Development Metanephric Distal Convoluted Tubule Development Metanephric Connecting Tubule Development Cochlea Development Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration
Pathways		TRP channels	Amyloid fiber formation
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Anxiety ( 31906708) Cancer ( 29299148) Mastocytosis ( 32752121)	Chronotype ( 27494321 30696823) Morning vs. evening chronotype ( 27494321)
Interacting Genes		17 interacting genes: CALB1 CALM1 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-8 MDFI MID2 NEDD4 NOTCH2NLA PDE9A PNMA1 PRKCA PTPN1 S100A10 SNCA TRAF1	6 interacting genes: CACNA1D IKBKG IMPA1 RANBP9 TRPV5 TRPV6
Entrez ID		55503	793
HPRD ID		05982	00229
Ensembl ID		ENSG00000165125	ENSG00000104327
Uniprot IDs		Q9H1D0	P05937
PDB IDs		6BO8 6BO9 6BOA 6D7S 6D7T 6E2F 7K4A 7K4B 7K4C 7K4D 7K4E 7K4F 7S88 7S89 7S8B 7S8C 8FOA 8FOB 8SP8 9CUH 9CUI 9CUJ 9CUK	6FIE
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Regulation Of Synaptic Plasticity Regulation Of Cell Communication Regulation Of Signaling Enzyme Binding Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Exocytosis Regulation Of Cell Junction Assembly Positive Regulation Of Cell Communication Positive Regulation Of Signaling Calyx Of Held Regulation Of Signal Transduction Regulation Of Synapse Organization Calcium Ion Binding Presynaptic Cytosol Postsynaptic Cytosol Transmembrane Transporter Binding Regulation Of Intracellular Signal Transduction Positive Regulation Of Synaptic Transmission Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Metanephric Connecting Tubule Development Terminal Bouton Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Presynaptic Endocytosis Protein-containing Complex Identical Protein Binding Protein Sequestering Activity Receptor Metabolic Process Formation Of Structure Involved In A Symbiotic Process Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Synapse Assembly Regulation Of Exocytosis Response To Fibroblast Growth Factor Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Phosphoprotein Binding Cytosol Modulation Of Chemical Synaptic Transmission Long-term Synaptic Potentiation Postsynapse Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Muscle System Process Regulation Of System Process	Calcium Ion Import Across Plasma Membrane Calcium Ion Import Into Cytosol Calcium Ion Import Calcium Ion Transmembrane Import Into Cytosol Calcium Channel Activity Inorganic Cation Import Across Plasma Membrane Import Across Plasma Membrane Monoatomic Ion Channel Activity Calcium Ion Transmembrane Transport Calcium Channel Complex Calcium Ion Transport Voltage-gated Calcium Channel Activity Involved SA Node Cell Action Potential Glycerol-2-phosphatase Activity Lithium Ion Binding Inositol Monophosphate 4-phosphatase Activity Inositol Monophosphate Phosphatase Activity Inositol Monophosphate 1-phosphatase Activity Glucose-1-phosphatase Activity Inositol Monophosphate 3-phosphatase Activity Fructose-1-phosphatase Activity Ubiquitin Ligase Complex Parathyroid Hormone Secretion Metal Ion Transport Import Into Cell Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Voltage-gated Calcium Channel Activity Involved In Cardiac Muscle Cell Action Potential Inositol Biosynthetic Process Glucose-6-phosphatase Activity Linear Polyubiquitin Binding Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Membrane Depolarization During SA Node Cell Action Potential Calmodulin Binding Metal Ion Binding Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Inositol Metabolic Process IkappaB Kinase Complex Calcium Ion Homeostasis Monoatomic Ion Transport L-type Voltage-gated Calcium Channel Complex Transferrin Receptor Binding Anoikis High Voltage-gated Calcium Channel Activity Calcium Ion Transport Into Cytosol Transmembrane Transport Alpha-actinin Binding Membrane Depolarization During Cardiac Muscle Cell Action Potential Ankyrin Binding
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