FBXW7 and MCL1

  • Number of citations of the paper that reports this interaction (PMID 22608923)
  • 17
  • Data Source:
  • BioGRID (enzymatic study)

FBXW7

MCL1

Gene Name F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase myeloid cell leukemia 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 33 interactors: ARL6IP1 CCNE1 CCNE2 CDC34 CREB3L1 CREB3L2 CUL1 EBNA1BP2 FAM101A GLMN GNB2L1 HEY1 HIPK2 JUN KIAA1875 KLF5 LINGO1 MCL1 MED13 MED13L MMS22L MYB MYC NOTCH1 NOTCH4 PARK2 PPARGC1A PSEN1 SHPRH SKP1 STOML1 SUMF2 UBE2D1 29 interactors: BAD BAK1 BAX BBC3 BCL2L1 BCL2L11 BID BIK BMF BOK CASP3 DAD1 FBXW7 GSK3A GSK3B HRK HUWE1 MAPK1 MAPK10 PCNA PIN1 PMAIP1 TNKS TP53 TPT1 TRAF6 UHRF2 USP9X VDAC1
Entrez ID 55294 4170
HPRD ID 05888 08870
Ensembl ID ENSG00000109670 ENSG00000143384
Uniprot IDs B7Z2C8 G0Z2K0 Q969H0 S4R3U4 C8YZ26 Q07820
PDB IDs 2OVP 2OVQ 2OVR 2KBW 2NL9 2NLA 2PQK 3D7V 3IO9 3KJ0 3KJ1 3KJ2 3KZ0 3MK8 3PK1 3TWU 4HW2 4HW3 4HW4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
34a  bcl6  bim  btk  buffering  dlbcl  doi  fluctuations  follicular  foxp1  gab1  immunoglobulins  intimately  leu  lymphocytic  mantle  marginal  mirnas  modulators  myb  niches  preview  pu  put  stochastic  subtle  summarizing  tcl1  zap 
Tagcloud (Difference) ?
bcl11b  cadherin  discovered  dnm2  druggable  exhibitedthe  fat1  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
34a  bcl6  bim  btk  buffering  dlbcl  doi  fluctuations  follicular  foxp1  gab1  immunoglobulins  intimately  leu  lymphocytic  mantle  marginal  mirnas  modulators  myb  niches  preview  pu  put  stochastic  subtle  summarizing  tcl1  zap 
Tagcloud (Intersection) ?