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MTPAP and CALCOCO2
Number of citations of the paper that reports this interaction (PMID
21903422
)
33
Data Source:
BioGRID
(affinity chromatography technology, pull down)
MTPAP
CALCOCO2
Gene Name
mitochondrial poly(A) polymerase
calcium binding and coiled-coil domain 2
Image
Gene Ontology Annotations
Cellular Component
Mitochondrion
Intracellular Membrane-bounded Organelle
Nucleus
Cytoplasm
Golgi Apparatus
Cytoskeleton
Membrane
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Molecular Function
Magnesium Ion Binding
UTP Binding
Polynucleotide Adenylyltransferase Activity
Protein Binding
ATP Binding
Manganese Ion Binding
Identical Protein Binding
Protein Homodimerization Activity
Poly(A) RNA Binding
Protein Binding
Protein Homodimerization Activity
Biological Process
Transcription, DNA-templated
MRNA Polyadenylation
Histone MRNA Catabolic Process
Viral Process
Response To Interferon-gamma
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
AZI2
CALCOCO2
TBK1
143 interactors:
ABLIM1
ADSL
AES
AKAP17A
AMMECR1
AP5B1
APEX2
ARHGEF39
ARHGEF5
ARNT2
BAHD1
BCL6B
BEX2
C20orf195
CBX8
CCDC185
CCDC33
CCNH
CEP57L1
CHCHD3
CPNE7
CWF19L2
DAXX
DAZAP2
DBNDD2
DCTN4
DCX
DDIT4L
DDX6
DOCK2
DUSP12
DUSP26
EEF1E1
ENKD1
EXOSC5
FAM107A
FAM161A
FAM168A
FAM189A2
FAM90A1
FARS2
FASTK
FBF1
FBXL18
FKBPL
FXR2
GABARAPL1
GABARAPL2
GATAD2B
GEMIN4
GIT2
GLYCTK
HDAC7
HOXB9
IKBKG
KANSL1
KAT7
KLHL42
LENG1
LGALS8
LIMS2
LITAF
LMF2
LMO2
LMO4
LNX1
LONRF1
LSM4
MAGOHB
MAVS
MCM10
METTL17
MID2
MOS
MTPAP
MVP
MXI1
MYO6
NAA10
NDN
NFU1
ORC5
PAPD4
PCGF1
PEF1
PEG10
PFDN5
PHF1
PIAS4
POLI
PPP1R18
PRKAB2
PRPF31
PSMA1
PSME4
PTBP1
PTBP2
RABL6
RB1CC1
RBM15
RHPN1
RIN1
RNF11
RPA2
RPL9
RPS27A
RTN4IP1
RTP5
SDCBP
SHC1
SLC15A3
SMARCD1
SMCP
SNRPB
SPATA24
SRI
STK16
TAX1BP1
TBC1D22B
TBK1
TBRG4
TCEB3B
TCL1A
TEKT3
TP53RK
TRAF2
TRAF4
TRAF6
UBAC2
UBB
UBC
VARS
VPS72
ZC2HC1C
ZNF101
ZNF205
ZNF337
ZNF408
ZNF426
ZNF451
ZNF564
ZNF581
ZNF638
Entrez ID
55149
10241
HPRD ID
15097
06846
Ensembl ID
ENSG00000107951
ENSG00000136436
Uniprot IDs
Q9NVV4
Q13137
PDB IDs
3PQ1
3VVV
3VVW
4GXL
4HAN
Enriched GO Terms of Interacting Partners
?
Dendritic Cell Proliferation
Type I Interferon Production
I-kappaB Kinase/NF-kappaB Signaling
Lymphocyte Proliferation
Mononuclear Cell Proliferation
Leukocyte Proliferation
Cytokine Production
Tumor Necrosis Factor Production
Interferon-alpha Production
Interleukin-6 Production
Immune System Process
Positive Regulation Of Interferon-beta Biosynthetic Process
Lymphocyte Activation
Leukocyte Activation
Viral Process
Interferon-gamma Production
Cell Activation
Positive Regulation Of Interferon-alpha Production
Cell Proliferation
Positive Regulation Of Interferon-beta Production
Innate Immune Response
Dendritic Cell Differentiation
Regulation Of Interferon-beta Production
Negative Regulation Of Type I Interferon Production
TRIF-dependent Toll-like Receptor Signaling Pathway
Defense Response To Gram-positive Bacterium
Positive Regulation Of Cytokine Biosynthetic Process
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Immune Response
Defense Response
Positive Regulation Of Type I Interferon Production
Positive Regulation Of Peptidyl-serine Phosphorylation
Toll-like Receptor 4 Signaling Pathway
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
I-kappaB Kinase/NF-kappaB Signaling
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Type I Interferon Production
MRNA Metabolic Process
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
JNK Cascade
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Protein Modification By Small Protein Conjugation
Activation Of MAPK Activity
Activation Of Innate Immune Response
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Signaling
Positive Regulation Of Protein Modification Process
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of Type I Interferon Production
Activation Of NF-kappaB-inducing Kinase Activity
Protein Ubiquitination
Toll-like Receptor Signaling Pathway
Positive Regulation Of MAP Kinase Activity
G1/S Transition Of Mitotic Cell Cycle
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Mitotic G1 DNA Damage Checkpoint
Tagcloud
?
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autophagy
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brains
clear
clearance
enhancement
expected
facilitating
flux
hippocampal
impairment
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localized
microglia
mouse
ndp52
p62
phosphorylated
plaques
reflecting
sqstm1
tau
vesicles
Tagcloud (Difference)
?
ad
astrocytes
atg
atgs
autophagic
autophagy
avs
beneficial
brains
clear
clearance
enhancement
expected
facilitating
flux
hippocampal
impairment
lc3
localized
microglia
mouse
ndp52
p62
phosphorylated
plaques
reflecting
sqstm1
tau
vesicles
Tagcloud (Intersection)
?