MTPAP

Gene Name		mitochondrial poly(A) polymerase
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Gene Ontology Annotations	Cellular Component	Mitochondrion Intracellular Membrane-bounded Organelle
	Molecular Function	Magnesium Ion Binding UTP Binding Polynucleotide Adenylyltransferase Activity Protein Binding ATP Binding Manganese Ion Binding Identical Protein Binding Protein Homodimerization Activity Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated MRNA Polyadenylation Histone MRNA Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: AZI2 CALCOCO2 TBK1
Entrez ID		55149
HPRD ID		15097
Ensembl ID		ENSG00000107951
Uniprot IDs		Q9NVV4
PDB IDs		3PQ1
Enriched GO Terms of Interacting Partners?		Dendritic Cell Proliferation Type I Interferon Production I-kappaB Kinase/NF-kappaB Signaling Lymphocyte Proliferation Mononuclear Cell Proliferation Leukocyte Proliferation Cytokine Production Tumor Necrosis Factor Production Interferon-alpha Production Interleukin-6 Production Immune System Process Positive Regulation Of Interferon-beta Biosynthetic Process Lymphocyte Activation Leukocyte Activation Viral Process Interferon-gamma Production Cell Activation Positive Regulation Of Interferon-alpha Production Cell Proliferation Positive Regulation Of Interferon-beta Production Innate Immune Response Dendritic Cell Differentiation Regulation Of Interferon-beta Production Negative Regulation Of Type I Interferon Production TRIF-dependent Toll-like Receptor Signaling Pathway Defense Response To Gram-positive Bacterium Positive Regulation Of Cytokine Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Immune Response Defense Response Positive Regulation Of Type I Interferon Production Positive Regulation Of Peptidyl-serine Phosphorylation Toll-like Receptor 4 Signaling Pathway
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