RNF31 and NR0B1

Number of citations of the paper that reports this interaction (PMID 19237537)
8

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		RNF31	NR0B1
Gene Name		ring finger protein 31	nuclear receptor subfamily 0, group B, member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex LUBAC Complex	Nucleus Nucleoplasm Cytoplasm Membrane Polysomal Ribosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Ubiquitin Binding	DNA Binding Steroid Hormone Receptor Activity Transcription Corepressor Activity RNA Binding Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding DNA Hairpin Binding Steroid Hormone Receptor Binding Protein Homodimerization Activity Sequence-specific DNA Binding AF-2 Domain Binding
	Biological Process	Protein Polyubiquitination CD40 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Linear Polyubiquitination	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Steroid Biosynthetic Process Spermatogenesis Protein Localization Gonad Development Male Gonad Development Gene Expression Hypothalamus Development Pituitary Gland Development Male Sex Determination Adrenal Gland Development Intracellular Receptor Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Leydig Cell Differentiation Response To Immobilization Stress Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Sertoli Cell Differentiation
Pathways
Drugs			Tretinoin Dexamethasone
Diseases
GWAS
Protein-Protein Interactions		27 interactors: AES ATN1 ATXN1 ATXN7 AZI2 CCDC24 GFI1B IKBKG KIF1A KRTAP9-2 NOS3 NR0B1 NR0B2 PITX1 PRKCA RBCK1 SMAD3 SNRPC SOCS3 TRAF1 TRIM25 TSSC4 UBC UBE2D1 UBE2D3 VASN VCP	16 interactors: AR COPS2 ESR1 ESR2 ESRRA ESRRG NR3C1 NR5A1 NRIP1 PGR POU5F1 PPARG RNF31 RORA SNW1 SREBF1
Entrez ID		55072	190
HPRD ID		11516	08362
Ensembl ID		ENSG00000092098
Uniprot IDs		Q96EP0	F1D8P4 P51843
PDB IDs		2CT7 4DBG 4JUY
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Signaling Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation RNA Biosynthetic Process Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Response To Abiotic Stimulus Regulation Of Apoptotic Process MyD88-independent Toll-like Receptor Signaling Pathway Cellular Response To Organic Substance Toll-like Receptor 3 Signaling Pathway Regulation Of Cell Death Protein Ubiquitination Signaling Toll-like Receptor 4 Signaling Pathway Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Response To Organic Substance Protein Modification By Small Protein Conjugation Cell Communication Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Immune System Process Apoptotic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels	Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Lipid Cellular Response To Steroid Hormone Stimulus Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Response To Steroid Hormone Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Response To Lipid Cellular Response To Organic Cyclic Compound Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Response To Organic Cyclic Compound Response To Hormone RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Signal Transduction Cellular Response To Organic Substance Signaling Positive Regulation Of Cellular Metabolic Process Cell Communication Nucleobase-containing Compound Metabolic Process Rhythmic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Organ Development Cellular Nitrogen Compound Metabolic Process Cellular Response To Stimulus System Development Response To Organic Substance Ovulation Cycle Process Nitrogen Compound Metabolic Process
Tagcloud ?		adjuvant antiestrogens arise aromatase associates atypical confirms cytosol decreases diagnostics e3 eralpha establishes estrogen facilitates initially insights ligase mono occupied promoters reduces stability stabilizes stabilizing therapeutics ubiquitin ubiquitination utmost	always cd99 chondrosarcoma comprising differentiate diffuse e2f3 es ewing ewsr1 exceptional extraskeletal fli1 gold immunohistochemical marker merkel mesenchymal myxoid neoplasm neuroblastomas nkx2 olfactory powerful reinforces round sarcoma singly srcts
Tagcloud (Difference) ?		adjuvant antiestrogens arise aromatase associates atypical confirms cytosol decreases diagnostics e3 eralpha establishes estrogen facilitates initially insights ligase mono occupied promoters reduces stability stabilizes stabilizing therapeutics ubiquitin ubiquitination utmost	always cd99 chondrosarcoma comprising differentiate diffuse e2f3 es ewing ewsr1 exceptional extraskeletal fli1 gold immunohistochemical marker merkel mesenchymal myxoid neoplasm neuroblastomas nkx2 olfactory powerful reinforces round sarcoma singly srcts
Tagcloud (Intersection) ?