TESC and HMG20A

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		TESC	HMG20A
Gene Name		tescalcin	high mobility group 20A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Plasma Membrane Lamellipodium Ruffle Membrane	Nucleus
	Molecular Function	Magnesium Ion Binding Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Phosphatase Inhibitor Activity Protein Homodimerization Activity	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Proliferation Male Gonad Development Positive Regulation Of Gene Expression Megakaryocyte Differentiation Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Protein Stabilization Protein Maturation Cellular Response To Retinoic Acid Protein Targeting To Plasma Membrane	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Negative Regulation Of Neuron Differentiation
Pathways
Drugs
Diseases
GWAS			Type 2 diabetes ( 21490949 22693455 21874001)
Protein-Protein Interactions		6 interactors: CCDC91 DYNLT3 HMG20A RAI1 SLC9A1 WBP11	19 interactors: ADD1 BRAP CCDC136 CCNK CFAP53 DTNB FMNL1 GTF2A1L HPCAL1 KPNA2 MAGOHB PTH2R RBM7 RPP30 RSPH9 SCNM1 SMAD4 SYTL4 TESC
Entrez ID		54997	10363
HPRD ID		11649	16116
Ensembl ID		ENSG00000088992	ENSG00000140382
Uniprot IDs		Q96BS2	Q9NP66
PDB IDs
Enriched GO Terms of Interacting Partners?		Sodium Ion Import Across Plasma Membrane Sodium Ion Import Cardiac Muscle Cell Contraction Regulation Of The Force Of Heart Contraction By Cardiac Conduction Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of The Force Of Heart Contraction Positive Regulation Of Calcineurin-NFAT Signaling Cascade Sodium Ion Export Positive Regulation Of NFAT Protein Import Into Nucleus Cellular Response To Acidic PH Positive Regulation Of Action Potential Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Membrane Potential Cellular Response To Electrical Stimulus Maintenance Of Cell Polarity Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Sodium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Hyaluronan Catabolic Process Cellular Response To PH Positive Regulation Of Sodium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Mitochondrial Membrane Permeability Response To Epinephrine Negative Regulation Of Multicellular Organism Growth Cellular Response To Antibiotic
Tagcloud ?		amiloride aml blasts cd122 chemorefractory clearing duplication exchanger flt3 fms hexamethylene hma inferior invariably itd lowered m13 molm mv4 nhe1 otherwise pathogenetic phi primed recapitulated sorafenib tescalcin underlie xenotransplantation
Tagcloud (Difference) ?		amiloride aml blasts cd122 chemorefractory clearing duplication exchanger flt3 fms hexamethylene hma inferior invariably itd lowered m13 molm mv4 nhe1 otherwise pathogenetic phi primed recapitulated sorafenib tescalcin underlie xenotransplantation
Tagcloud (Intersection) ?