TESC and CCDC91

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TESC	CCDC91
Gene Name		tescalcin	coiled-coil domain containing 91
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Plasma Membrane Lamellipodium Ruffle Membrane	Nucleoplasm Golgi Apparatus Membrane
	Molecular Function	Magnesium Ion Binding Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Phosphatase Inhibitor Activity Protein Homodimerization Activity	Identical Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Proliferation Male Gonad Development Positive Regulation Of Gene Expression Megakaryocyte Differentiation Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Protein Stabilization Protein Maturation Cellular Response To Retinoic Acid Protein Targeting To Plasma Membrane	Protein Transport
Pathways
Drugs
Diseases
GWAS			Height ( 20881960 23563607) Obesity-related traits ( 23251661)
Protein-Protein Interactions		6 interactors: CCDC91 DYNLT3 HMG20A RAI1 SLC9A1 WBP11	6 interactors: ECT2 EWSR1 GGA1 GGA2 SYNRG TESC
Entrez ID		54997	55297
HPRD ID		11649	16905
Ensembl ID		ENSG00000088992	ENSG00000123106
Uniprot IDs		Q96BS2	Q05D28 Q7Z6B0
PDB IDs			1OM9
Enriched GO Terms of Interacting Partners?		Sodium Ion Import Across Plasma Membrane Sodium Ion Import Cardiac Muscle Cell Contraction Regulation Of The Force Of Heart Contraction By Cardiac Conduction Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of The Force Of Heart Contraction Positive Regulation Of Calcineurin-NFAT Signaling Cascade Sodium Ion Export Positive Regulation Of NFAT Protein Import Into Nucleus Cellular Response To Acidic PH Positive Regulation Of Action Potential Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Membrane Potential Cellular Response To Electrical Stimulus Maintenance Of Cell Polarity Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Sodium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Hyaluronan Catabolic Process Cellular Response To PH Positive Regulation Of Sodium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Mitochondrial Membrane Permeability Response To Epinephrine Negative Regulation Of Multicellular Organism Growth Cellular Response To Antibiotic	Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Protein Transport Cellular Protein Localization Intracellular Transport Establishment Of Localization In Cell Positive Regulation Of Sodium:proton Antiporter Activity Cellular Localization Regulation Of Sodium:proton Antiporter Activity Transport Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Regulation Of Proton Transport Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Activation Of Rac GTPase Activity Vesicle-mediated Transport Positive Regulation Of Sodium Ion Transmembrane Transport
Tagcloud ?		amiloride aml blasts cd122 chemorefractory clearing duplication exchanger flt3 fms hexamethylene hma inferior invariably itd lowered m13 molm mv4 nhe1 otherwise pathogenetic phi primed recapitulated sorafenib tescalcin underlie xenotransplantation
Tagcloud (Difference) ?		amiloride aml blasts cd122 chemorefractory clearing duplication exchanger flt3 fms hexamethylene hma inferior invariably itd lowered m13 molm mv4 nhe1 otherwise pathogenetic phi primed recapitulated sorafenib tescalcin underlie xenotransplantation
Tagcloud (Intersection) ?