TESC and DYNLT3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TESC	DYNLT3
Gene Name		tescalcin	dynein, light chain, Tctex-type 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Plasma Membrane Lamellipodium Ruffle Membrane	Kinetochore Condensed Chromosome Kinetochore Nucleus Cytoplasmic Dynein Complex Microtubule
	Molecular Function	Magnesium Ion Binding Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Phosphatase Inhibitor Activity Protein Homodimerization Activity	Motor Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Proliferation Male Gonad Development Positive Regulation Of Gene Expression Megakaryocyte Differentiation Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Protein Stabilization Protein Maturation Cellular Response To Retinoic Acid Protein Targeting To Plasma Membrane	Transport Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Metabolic Process Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CCDC91 DYNLT3 HMG20A RAI1 SLC9A1 WBP11	7 interactors: CD5 DYNC1I1 DYNC1I2 NIF3L1 PVR TESC VDAC1
Entrez ID		54997	6990
HPRD ID		11649	02249
Ensembl ID		ENSG00000088992	ENSG00000165169
Uniprot IDs		Q96BS2	P51808 Q6ICS3
PDB IDs
Enriched GO Terms of Interacting Partners?		Sodium Ion Import Across Plasma Membrane Sodium Ion Import Cardiac Muscle Cell Contraction Regulation Of The Force Of Heart Contraction By Cardiac Conduction Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of The Force Of Heart Contraction Positive Regulation Of Calcineurin-NFAT Signaling Cascade Sodium Ion Export Positive Regulation Of NFAT Protein Import Into Nucleus Cellular Response To Acidic PH Positive Regulation Of Action Potential Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Membrane Potential Cellular Response To Electrical Stimulus Maintenance Of Cell Polarity Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Sodium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Hyaluronan Catabolic Process Cellular Response To PH Positive Regulation Of Sodium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Mitochondrial Membrane Permeability Response To Epinephrine Negative Regulation Of Multicellular Organism Growth Cellular Response To Antibiotic	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Viral Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Susceptibility To T Cell Mediated Cytotoxicity 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Dihydrobiopterin Metabolic Process Positive Regulation Of Sodium:proton Antiporter Activity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immune System Process Immune System Process Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Immune Response To Tumor Cell Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Antigen Processing And Presentation Microtubule-based Movement Regulation Of Proton Transport Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Transmembrane Transport Regulation Of Immune System Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Megakaryocyte Differentiation Transport Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Ion Transmembrane Transport Megakaryocyte Differentiation Regulation Of Natural Killer Cell Mediated Cytotoxicity Movement Of Cell Or Subcellular Component Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Sodium Ion Transmembrane Transporter Activity
Tagcloud ?		amiloride aml blasts cd122 chemorefractory clearing duplication exchanger flt3 fms hexamethylene hma inferior invariably itd lowered m13 molm mv4 nhe1 otherwise pathogenetic phi primed recapitulated sorafenib tescalcin underlie xenotransplantation	associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll1 dynll2 dynlrb1 dynlrb2 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Difference) ?		amiloride aml blasts cd122 chemorefractory clearing duplication exchanger flt3 fms hexamethylene hma inferior invariably itd lowered m13 molm mv4 nhe1 otherwise pathogenetic phi primed recapitulated sorafenib tescalcin underlie xenotransplantation	associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll1 dynll2 dynlrb1 dynlrb2 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Intersection) ?