TESC and RAI1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TESC	RAI1
Gene Name		tescalcin	retinoic acid induced 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Plasma Membrane Lamellipodium Ruffle Membrane	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Magnesium Ion Binding Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Phosphatase Inhibitor Activity Protein Homodimerization Activity	Zinc Ion Binding Enhancer Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Proliferation Male Gonad Development Positive Regulation Of Gene Expression Megakaryocyte Differentiation Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Protein Stabilization Protein Maturation Cellular Response To Retinoic Acid Protein Targeting To Plasma Membrane	Skeletal System Development Regulation Of Transcription From RNA Polymerase II Promoter Circadian Regulation Of Gene Expression Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Parkinson's disease ( 21738487)
Protein-Protein Interactions		6 interactors: CCDC91 DYNLT3 HMG20A RAI1 SLC9A1 WBP11	15 interactors: CASP2 CDKN1A DDIT3 GADD45A GATA1 GLI1 GSK3B LZTR1 MAML3 MAPK8IP2 PIN1 RPS6KA5 TESC TTR ZNF496
Entrez ID		54997	10743
HPRD ID		11649	07406
Ensembl ID		ENSG00000088992	ENSG00000108557
Uniprot IDs		Q96BS2	Q7Z5J4
PDB IDs
Enriched GO Terms of Interacting Partners?		Sodium Ion Import Across Plasma Membrane Sodium Ion Import Cardiac Muscle Cell Contraction Regulation Of The Force Of Heart Contraction By Cardiac Conduction Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of The Force Of Heart Contraction Positive Regulation Of Calcineurin-NFAT Signaling Cascade Sodium Ion Export Positive Regulation Of NFAT Protein Import Into Nucleus Cellular Response To Acidic PH Positive Regulation Of Action Potential Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Membrane Potential Cellular Response To Electrical Stimulus Maintenance Of Cell Polarity Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Sodium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Hyaluronan Catabolic Process Cellular Response To PH Positive Regulation Of Sodium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Mitochondrial Membrane Permeability Response To Epinephrine Negative Regulation Of Multicellular Organism Growth Cellular Response To Antibiotic	Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Phosphorylation Regulation Of Protein Kinase Activity Cellular Response To Stimulus Regulation Of Kinase Activity Cellular Response To Organic Substance Signaling Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Protein Kinase Activity Cell Communication Neurotrophin Signaling Pathway Negative Regulation Of Kinase Activity Cellular Response To Mechanical Stimulus ER Overload Response Cellular Response To Stress Positive Regulation Of Transferase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Programmed Cell Death Signal Transduction In Response To DNA Damage Positive Regulation Of Cell Death Negative Regulation Of Transferase Activity Signal Transduction Regulation Of Catalytic Activity Regulation Of Cellular Process Negative Regulation Of Protein Phosphorylation Response To Stimulus Response To Organic Substance Apoptotic Signaling Pathway Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Response To Stress Intracellular Signal Transduction Megakaryocyte Differentiation
Tagcloud ?		amiloride aml blasts cd122 chemorefractory clearing duplication exchanger flt3 fms hexamethylene hma inferior invariably itd lowered m13 molm mv4 nhe1 otherwise pathogenetic phi primed recapitulated sorafenib tescalcin underlie xenotransplantation	comprise coordinate degrade demonstration divalent dom3z eukaryotes exclusive exoribonuclease exoribonucleases homologue landscape messenger mutagenesis nucleases pilt pin pocket pombe possesses pyrophosphohydrolase rat1 refs schizosaccharomyces termination triphosphorylated unexpectedly xrn2 xrns
Tagcloud (Difference) ?		amiloride aml blasts cd122 chemorefractory clearing duplication exchanger flt3 fms hexamethylene hma inferior invariably itd lowered m13 molm mv4 nhe1 otherwise pathogenetic phi primed recapitulated sorafenib tescalcin underlie xenotransplantation	comprise coordinate degrade demonstration divalent dom3z eukaryotes exclusive exoribonuclease exoribonucleases homologue landscape messenger mutagenesis nucleases pilt pin pocket pombe possesses pyrophosphohydrolase rat1 refs schizosaccharomyces termination triphosphorylated unexpectedly xrn2 xrns
Tagcloud (Intersection) ?