PPOX and HNRNPD

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		PPOX	HNRNPD
Gene Name		protoporphyrinogen oxidase	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
Image
Gene Ontology Annotations	Cellular Component	Mitochondrial Intermembrane Space Intrinsic Component Of Mitochondrial Inner Membrane Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane	Nucleus Nucleoplasm Cytosol Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	Oxygen-dependent Protoporphyrinogen Oxidase Activity Flavin Adenine Dinucleotide Binding	Nucleotide Binding RNA Binding Protein Binding Telomeric DNA Binding Poly(A) RNA Binding
	Biological Process	Porphyrin-containing Compound Metabolic Process Porphyrin-containing Compound Biosynthetic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Response To Drug Small Molecule Metabolic Process Oxidation-reduction Process	MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing RNA Catabolic Process RNA Splicing Gene Expression Regulation Of Circadian Rhythm Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Transcription, DNA-templated Circadian Regulation Of Translation
Pathways		Heme biosynthesis Metabolism of porphyrins	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: COPS5 HAP1 HNRNPD IMMT	92 interactors: ABCC10 ACTB ARF4 B3GAT3 BCL2 BET1L BRCA1 C1QBP CAPN1 CD81 CD97 CINP COG7 COL18A1 CSDE1 CTSB CUTA DGCR2 DHX30 EEF2 EIF4G1 ERG EXOSC4 FBXL15 FLNA GSK3B GTF3C3 GTSE1 GUK1 HBZ HDAC1 HIRA HMGA1 HNRNPC HNRNPF HNRNPH3 HNRNPK HNRNPU HSPA4 HSPB1 HSPB2 IGF2BP2 IL7R IMMP2L IMMT ING4 LDHA LSM5 MAP2K1 MAPK6 MEOX2 MPP1 MTA2 MYC NTMT1 P4HB PABPC1 PCBP1 PCBP2 PCSK7 PDLIM7 PEX10 PPOX PRDX3 PRKACA PTBP2 PYCR1 RALY RPSA SAFB SDF2 SEPT9 SF3B4 SFN SHISA5 SLC27A5 SLC3A2 SNAPC4 SNRPC SREK1 SUMO4 SYNCRIP TMEM261 TNPO1 TRN-GTT2-1 TSEN34 U2AF2 UBE2I UQCRC1 VEGFA VHL YBX1
Entrez ID		5498	3184
HPRD ID		02953	03206
Ensembl ID		ENSG00000143224
Uniprot IDs		B3KT30 B4DY76 P50336	Q14103
PDB IDs		3NKS 4IVM 4IVO	1HD0 1HD1 1IQT 1WTB 1X0F 2Z5N
Enriched GO Terms of Interacting Partners?		Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Cilium Assembly Exosomal Secretion Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Circadian Regulation Of Translation Exocytosis Cullin Deneddylation Hypothalamus Cell Differentiation Negative Regulation Of Beta-amyloid Formation Protein Deneddylation Retrograde Axon Cargo Transport Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Microtubule-based Movement Positive Regulation Of Synaptic Transmission, GABAergic Secretion By Cell Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Smooth Muscle Cell Migration Mitochondrial Calcium Ion Homeostasis DNA Demethylation Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Telomere Maintenance Via Semi-conservative Replication Transcription, DNA-templated Regulation Of Beta-amyloid Formation Regulation Of Cilium Assembly RNA Biosynthetic Process Nuclear DNA Replication Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Amyloid Precursor Protein Catabolic Process Telomere Maintenance Via Recombination Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Secretion Hypothalamus Development Positive Regulation Of Organelle Assembly Positive Regulation Of Cell Cycle G1/S Phase Transition Anterograde Axon Cargo Transport Positive Regulation Of Cellular Metabolic Process Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Cellular Homeostasis DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cation Channel Activity	MRNA Metabolic Process RNA Splicing MRNA Processing RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Heterocycle Metabolic Process Cellular Metabolic Process Gene Expression Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Metabolic Process MRNA Stabilization Response To Stress Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression CRD-mediated MRNA Stabilization Cellular Process Positive Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Protein Export From Nucleus Nuclear-transcribed MRNA Catabolic Process Regulation Of Apoptotic Process MRNA Catabolic Process Viral Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Positive Regulation Of Cellular Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Organelle Organization Regulation Of Metabolic Process Response To Wounding Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Death RNA Catabolic Process Negative Regulation Of RNA Splicing Chromatin Remodeling Positive Regulation Of Metabolic Process Positive Regulation Of Mitochondrion Organization Regulation Of Translation
Tagcloud ?		1082dupc ahp ahps aip biosynthetic cancerous catalyzing complication g111r germline hcc hccs heme hit hmbs hydroxymethylbilane intermittent l220x l416x oxidase pathomechanisms porphyria porphyrias protoporphyrinogen respective somatic suppressors variegate vp	abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Difference) ?		1082dupc ahp ahps aip biosynthetic cancerous catalyzing complication g111r germline hcc hccs heme hit hmbs hydroxymethylbilane intermittent l220x l416x oxidase pathomechanisms porphyria porphyrias protoporphyrinogen respective somatic suppressors variegate vp	abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Intersection) ?