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DUSP10 and SLX1B
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
DUSP10
SLX1B
Gene Name
dual specificity phosphatase 10
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Slx1-Slx4 Complex
Molecular Function
Phosphoprotein Phosphatase Activity
Protein Tyrosine Phosphatase Activity
Protein Tyrosine/serine/threonine Phosphatase Activity
Phosphatase Activity
MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
MAP Kinase Phosphatase Activity
Protein Binding
Crossover Junction Endodeoxyribonuclease Activity
5'-flap Endonuclease Activity
Metal Ion Binding
Biological Process
Inactivation Of MAPK Activity
Regulation Of Adaptive Immune Response
Protein Dephosphorylation
Response To Stress
JNK Cascade
Response To Lipopolysaccharide
Peptidyl-tyrosine Dephosphorylation
Negative Regulation Of JUN Kinase Activity
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
Negative Regulation Of JNK Cascade
Oligodendrocyte Differentiation
Negative Regulation Of Oligodendrocyte Differentiation
Negative Regulation Of Respiratory Burst Involved In Inflammatory Response
Regulation Of Brown Fat Cell Differentiation
Double-strand Break Repair Via Homologous Recombination
DNA Catabolic Process, Endonucleolytic
DNA Repair
DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing
Pathways
Drugs
Diseases
GWAS
Colorectal cancer (
20972440
)
Protein-Protein Interactions
12 interactors:
CMTM6
FHL2
FN1
HTT
MAPK10
MAPK11
MAPK14
MAPK3
MAPK8
RPS11
SLX1B
SNX2
3 interactors:
DUSP10
THAP11
TUBA1B
Entrez ID
11221
79008
HPRD ID
12320
14673
Ensembl ID
ENSG00000143507
ENSG00000181625
Uniprot IDs
B4DDQ0
Q9Y6W6
Q9BQ83
PDB IDs
1ZZW
2OUC
2OUD
3TG1
Enriched GO Terms of Interacting Partners
?
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor Signaling Pathway
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
MAPK Cascade
Regulation Of Innate Immune Response
Signal Transduction By Phosphorylation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Activation Of MAPK Activity
Immune Response-regulating Signaling Pathway
JUN Phosphorylation
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of MAP Kinase Activity
Neurotrophin Signaling Pathway
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Immune Response
Regulation Of MAP Kinase Activity
Positive Regulation Of Signal Transduction
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Defense Response
Innate Immune Response
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Immune Response
Cellular Response To Lipid
Cellular Response To Stress
Positive Regulation Of Catalytic Activity
Positive Regulation Of Immune System Process
Regulation Of Catalytic Activity
Positive Regulation Of Metabolic Process
Positive Regulation Of MAPK Cascade
Cellular Response To Lipopolysaccharide
Response To Radiation
Response To Stress
Cellular Response To Molecule Of Bacterial Origin
Positive Regulation Of Protein Kinase Activity
Negative Regulation Of Respiratory Burst Involved In Inflammatory Response
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
Regulation Of Brown Fat Cell Differentiation
Regulation Of Respiratory Burst
Negative Regulation Of JUN Kinase Activity
Tagcloud
?
bc
bcs
dephosphorylate
differentially
distant
dmfs
dusp4
dusp6
enpp1
erbb2
erk
ihc
inpp4b
microarray
microarrays
motility
multiphosphatase
phosphatases
phosphatome
phospho
ppapdc1a
relevance
seemed
series
sharing
signature
subgroups
unlike
warranted
Tagcloud (Difference)
?
bc
bcs
dephosphorylate
differentially
distant
dmfs
dusp4
dusp6
enpp1
erbb2
erk
ihc
inpp4b
microarray
microarrays
motility
multiphosphatase
phosphatases
phosphatome
phospho
ppapdc1a
relevance
seemed
series
sharing
signature
subgroups
unlike
warranted
Tagcloud (Intersection)
?