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SPDL1 and TRAF4
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SPDL1
TRAF4
Gene Name
spindle apparatus coiled-coil protein 1
TNF receptor-associated factor 4
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Spindle Pole
Condensed Chromosome Outer Kinetochore
Nucleus
Microtubule Organizing Center
Cytosol
Nucleus
Cytoplasm
Cytoskeleton
Plasma Membrane
Tight Junction
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Enzyme Binding
Kinetochore Binding
DNA Binding
Ubiquitin-protein Transferase Activity
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
WW Domain Binding
Biological Process
Establishment Of Mitotic Spindle Orientation
Mitotic Cell Cycle
Mitotic Metaphase Plate Congression
Spindle Checkpoint
Protein Localization To Kinetochore
Cell Division
Apoptotic Process
Signal Transduction
Activation Of NF-kappaB-inducing Kinase Activity
Respiratory Gaseous Exchange
Protein Ubiquitination
Respiratory Tube Development
Regulation Of Apoptotic Process
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of JNK Cascade
Positive Regulation Of Protein Homodimerization Activity
Pathways
Mitotic Prometaphase
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Mitotic Anaphase
Mitotic Metaphase and Anaphase
Cell Cycle, Mitotic
M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions
9 interactors:
CA8
DYX1C1
GPS2
ITSN1
KIAA1377
PPP1R18
RTP5
TRAF4
USP15
69 interactors:
ALKBH4
ARNT2
BAHD1
BANP
BCKDK
BCL6B
BYSL
CALCOCO2
CBL
CBLC
CCHCR1
CENPE
CHUK
DTX3
EXOC7
FBXL18
FTH1
GORASP2
GPRASP1
HOMEZ
IRAK1
ISYNA1
KANSL1
KDM1A
KRT31
KRT40
LTBR
MAGED1
MAP3K4
MRPL28
NCF1
NGFR
NGFRAP1
NOS1AP
NPAS2
PDE4DIP
PKD1P1
PLSCR1
PSMC3
QARS
REXO1L6P
RNF114
RPS6KB1
SIGLEC7
SMURF1
SMURF2
SORBS2
SPDL1
SUMO1
TARBP2
TBC1D7
TBC1D8
TGFB1I1
TICAM1
TNFRSF4
TP53BP2
TRAF6
TRIM37
TYK2
UBE2I
UBL4A
UBL4B
USP7
WBP11
WWP1
WWP2
ZNF3
ZNF512B
ZNF581
Entrez ID
54908
9618
HPRD ID
08623
03915
Ensembl ID
ENSG00000040275
ENSG00000076604
Uniprot IDs
Q96EA4
Q9BUZ4
PDB IDs
2EOD
2YUC
4M4E
Enriched GO Terms of Interacting Partners
?
Regulation Of Signal Transduction
Histone H2B Conserved C-terminal Lysine Deubiquitination
Regulation Of Signaling
Regulation Of JNK Cascade
Intracellular Signal Transduction
Regulation Of Stress-activated MAPK Cascade
Regulation Of Cellular Protein Metabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Inner Dynein Arm Assembly
Regulation Of Protein Metabolic Process
Outer Dynein Arm Assembly
Monoubiquitinated Protein Deubiquitination
Positive Regulation Of Protein Homodimerization Activity
Protein Modification By Small Protein Conjugation
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Ubiquitination
Regulation Of Gene Expression
Regulation Of Signal Transduction
Regulation Of Metabolic Process
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Signaling
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Response To Growth Factor
Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Ubiquitin-dependent SMAD Protein Catabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Signal Transduction
Cellular Protein Modification Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Protein Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Growth Factor Stimulus
Regulation Of Innate Immune Response
Negative Regulation Of Transcription, DNA-templated
Response To Organic Substance
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Programmed Cell Death
Proteolysis Involved In Cellular Protein Catabolic Process
Response To Cytokine
Cellular Protein Catabolic Process
Cell Death
Death
Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Protein Catabolic Process
Tagcloud
?
bcr
cart
cd40
cd54
cd95
ciap2
define
dr3
driven
effector
engagement
fas
icam
linking
mapk
mapkapk
minimal
p38
permeable
perturbed
potentiating
requirement
responsive
sb203580
selectively
stimulates
tonsillar
traf1
unaffected
Tagcloud (Difference)
?
bcr
cart
cd40
cd54
cd95
ciap2
define
dr3
driven
effector
engagement
fas
icam
linking
mapk
mapkapk
minimal
p38
permeable
perturbed
potentiating
requirement
responsive
sb203580
selectively
stimulates
tonsillar
traf1
unaffected
Tagcloud (Intersection)
?