SPDL1 and GPS2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SPDL1	GPS2
Gene Name		spindle apparatus coiled-coil protein 1	G protein pathway suppressor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Condensed Chromosome Outer Kinetochore Nucleus Microtubule Organizing Center Cytosol	Nucleoplasm Transcriptional Repressor Complex
	Molecular Function	Protein Binding Enzyme Binding Kinetochore Binding	Transcription Corepressor Activity GTPase Inhibitor Activity Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Mitotic Metaphase Plate Congression Spindle Checkpoint Protein Localization To Kinetochore Cell Division	Negative Regulation Of Transcription From RNA Polymerase II Promoter Inactivation Of MAPK Activity Chromatin Organization Cell Cycle JNK Cascade Negative Regulation Of JNK Cascade
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CA8 DYX1C1 GPS2 ITSN1 KIAA1377 PPP1R18 RTP5 TRAF4 USP15	23 interactors: ATF4 C19orf57 CCNA1 CHD3 CNOT2 EP300 GOLGA2 HDAC1 HDAC3 KRT31 MAP3K7CL NCOR1 NR0B2 PBK RALBP1 RBPMS SESTD1 SETDB1 SPDL1 TBL1X TBL1XR1 TFIP11 TP53
Entrez ID		54908	2874
HPRD ID		08623	11878
Ensembl ID		ENSG00000040275	ENSG00000132522
Uniprot IDs		Q96EA4	Q13227
PDB IDs			2L5G
Enriched GO Terms of Interacting Partners?		Regulation Of Signal Transduction Histone H2B Conserved C-terminal Lysine Deubiquitination Regulation Of Signaling Regulation Of JNK Cascade Intracellular Signal Transduction Regulation Of Stress-activated MAPK Cascade Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Inner Dynein Arm Assembly Regulation Of Protein Metabolic Process Outer Dynein Arm Assembly Monoubiquitinated Protein Deubiquitination Positive Regulation Of Protein Homodimerization Activity	Notch Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromosome Organization Transcription, DNA-templated Circadian Rhythm Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Rhythmic Process Histone Deacetylation Protein Deacetylation Negative Regulation Of Cellular Metabolic Process Circadian Regulation Of Gene Expression Regulation Of Gene Expression Histone Modification Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cell Cycle Process Macromolecule Biosynthetic Process Mitotic Cell Cycle Organelle Organization Nucleobase-containing Compound Metabolic Process Histone H3-K9 Modification Regulation Of Metabolic Process Negative Regulation Of Stress-activated MAPK Cascade Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Deacetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process
Tagcloud ?			abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps1 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank
Tagcloud (Difference) ?			abnormal assigned calculated cop count css escc esophageal esophagectomy follows glasgow gps0 gps1 hypoalbuminemia indexes kaplan log lymphocyte meier neutrophil nlr nlr0 nlr1 nlr2 platelet predicts prognostic rank
Tagcloud (Intersection) ?