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RRN3 and POLR1B
Number of citations of the paper that reports this interaction (PMID
15004009
)
81
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology)
HPRD
(in vivo, in vitro)
RRN3
POLR1B
Gene Name
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
polymerase (RNA) I polypeptide B, 128kDa
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Nucleoplasm
Nucleolus
DNA-directed RNA Polymerase I Complex
Cytoplasm
Molecular Function
RNA Polymerase Binding
RNA Polymerase I Activity
DNA Binding
Protein Binding
Ribonucleoside Binding
Metal Ion Binding
Biological Process
In Utero Embryonic Development
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Nucleolus Organization
Cytoplasm Organization
Cell Proliferation
Gene Expression
Ribosome Biogenesis
Positive Regulation Of Transcription, DNA-templated
Homeostasis Of Number Of Cells
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of DNA-templated Transcription, Initiation
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Embryo Implantation
RRNA Transcription
Gene Expression
Nucleologenesis
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Pathways
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Promoter Clearance
NoRC negatively regulates rRNA expression
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription
RNA Polymerase I Transcription Termination
RNA Polymerase I Promoter Escape
RNA Polymerase I Promoter Clearance
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
CCNE1
CDK2
EIF3L
MYO1C
POLR1A
POLR1B
PPP2R2A
TAF1A
TAF1B
TAF1C
14 interactors:
AKT2
CCND1
EIF3L
ESR1
GIT2
HDAC6
LDB1
LZTR1
MED20
NFKBIB
POLR1E
RPL37
RRN3
ZNF207
Entrez ID
54700
84172
HPRD ID
12004
06852
Ensembl ID
ENSG00000085721
ENSG00000125630
Uniprot IDs
F5H148
Q9NYV6
Q9H9Y6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription From RNA Polymerase I Promoter
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
DNA-templated Transcription, Elongation
Regulation Of Gene Expression, Epigenetic
DNA-templated Transcription, Initiation
Chromatin Silencing At RDNA
Chromatin Silencing
Gene Silencing
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
RRNA Transcription
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Metabolic Process
Nucleologenesis
RNA Metabolic Process
RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript
G2/M Transition Of Mitotic Cell Cycle
Nucleus Organization
Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Transcription, DNA-templated
RNA Biosynthetic Process
Positive Regulation Of DNA-dependent DNA Replication Initiation
G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway
Mitotic Cell Cycle Process
Post-embryonic Hemopoiesis
Nucleolus Organization
Cellular Metabolic Process
Mitotic Cell Cycle
Regulation Of DNA-dependent DNA Replication Initiation
Mitotic Nuclear Envelope Reassembly
Glomerular Visceral Epithelial Cell Development
Regulation Of Tight Junction Assembly
Metabolic Process
Nuclear Envelope Reassembly
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
RNA Biosynthetic Process
Gene Expression
Regulation Of Metabolic Process
Biosynthetic Process
DNA-templated Transcription, Initiation
Transcription, DNA-templated
RNA Metabolic Process
Mammary Gland Epithelium Development
Mammary Gland Epithelial Cell Proliferation
Transcription Initiation From RNA Polymerase I Promoter
Mammary Gland Development
Transcription From RNA Polymerase I Promoter
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Chromosome Organization
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Mammary Gland Lobule Development
Mammary Gland Alveolus Development
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Chromatin Organization
Histone H3-K4 Acetylation
Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery
Hsp90 Deacetylation
Negative Regulation Of Gene Expression
Regulation Of Protein Metabolic Process
Regulation Of Oxidoreductase Activity
Positive Regulation Of Type I Interferon Production
Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Chaperone-mediated Protein Complex Assembly
RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript
Positive Regulation Of Hemoglobin Biosynthetic Process
Polyubiquitinated Misfolded Protein Transport
Epithelial Cell Proliferation
Regulation Of Cell Cycle Arrest
Positive Regulation Of Metabolic Process
Re-entry Into Mitotic Cell Cycle
Prostate Epithelial Cord Elongation
Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Cellular Response To Topologically Incorrect Protein
Regulation Of Type I Interferon Production
Tagcloud
?
architecture
assemble
assembles
assembly
binds
biochemical
cf
comprising
conserved
cross
extend
insight
interconnected
linking
network
orthologous
pol
preinitiation
providing
rrn11
rrn6
rrn7
sl1
subunits
tata
tbp
tfiib
upstream
validated
Tagcloud (Difference)
?
architecture
assemble
assembles
assembly
binds
biochemical
cf
comprising
conserved
cross
extend
insight
interconnected
linking
network
orthologous
pol
preinitiation
providing
rrn11
rrn6
rrn7
sl1
subunits
tata
tbp
tfiib
upstream
validated
Tagcloud (Intersection)
?