POLR1B and RPL37

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		POLR1B	RPL37
Gene Name		polymerase (RNA) I polypeptide B, 128kDa	ribosomal protein L37
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus DNA-directed RNA Polymerase I Complex Cytoplasm	Cytosol Cytosolic Large Ribosomal Subunit
	Molecular Function	RNA Polymerase I Activity DNA Binding Protein Binding Ribonucleoside Binding Metal Ion Binding	RNA Binding Structural Constituent Of Ribosome RRNA Binding Metal Ion Binding
	Biological Process	Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Embryo Implantation RRNA Transcription Gene Expression Nucleologenesis Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: AKT2 CCND1 EIF3L ESR1 GIT2 HDAC6 LDB1 LZTR1 MED20 NFKBIB POLR1E RPL37 RRN3 ZNF207	5 interactors: APP POLR1B SQSTM1 TCF3 WIF1
Entrez ID		84172	6167
HPRD ID		06852	16047
Ensembl ID		ENSG00000125630
Uniprot IDs		Q9H9Y6	P61927
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression RNA Biosynthetic Process Gene Expression Regulation Of Metabolic Process Biosynthetic Process DNA-templated Transcription, Initiation Transcription, DNA-templated RNA Metabolic Process Mammary Gland Epithelium Development Mammary Gland Epithelial Cell Proliferation Transcription Initiation From RNA Polymerase I Promoter Mammary Gland Development Transcription From RNA Polymerase I Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromosome Organization Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Mammary Gland Lobule Development Mammary Gland Alveolus Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Chromatin Organization Histone H3-K4 Acetylation Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Hsp90 Deacetylation Negative Regulation Of Gene Expression Regulation Of Protein Metabolic Process Regulation Of Oxidoreductase Activity Positive Regulation Of Type I Interferon Production Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Chaperone-mediated Protein Complex Assembly RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript Positive Regulation Of Hemoglobin Biosynthetic Process Polyubiquitinated Misfolded Protein Transport Epithelial Cell Proliferation Regulation Of Cell Cycle Arrest Positive Regulation Of Metabolic Process Re-entry Into Mitotic Cell Cycle Prostate Epithelial Cord Elongation Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Cellular Response To Topologically Incorrect Protein Regulation Of Type I Interferon Production	Nucleologenesis Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Developmental Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Signal Transduction Regulation Of Cell Cycle Phase Transition Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axial Mesoderm Morphogenesis Nucleolus Organization Regulation Of Signaling Wnt Signaling Pathway Immunoglobulin V(D)J Recombination Axon Choice Point Recognition Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Cycle Regulation Of Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Neuron Remodeling Axial Mesoderm Development B Cell Lineage Commitment Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Macroautophagy Peyer's Patch Development Posttranscriptional Regulation Of Gene Expression Natural Killer Cell Differentiation Cellular Copper Ion Homeostasis Response To External Stimulus Anterior/posterior Axis Specification, Embryo Regulation Of Cell Cycle Process Regulation Of Transcription From RNA Polymerase II Promoter RRNA Transcription Copper Ion Homeostasis Suckling Behavior Regulation Of Neuron Differentiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Stem Cell Maintenance Termination Of RNA Polymerase I Transcription V(D)J Recombination Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Neuron Maturation
Tagcloud ?			aforementioned bind biogenesis downregulate e3 ectopically employ flag ha ligase mdm2 mdmx nucleolus null p53 relevantly respective revealing ribosomal ribosome rps rps15 rps20 stabilization stabilize surveillance tagged ways
Tagcloud (Difference) ?			aforementioned bind biogenesis downregulate e3 ectopically employ flag ha ligase mdm2 mdmx nucleolus null p53 relevantly respective revealing ribosomal ribosome rps rps15 rps20 stabilization stabilize surveillance tagged ways
Tagcloud (Intersection) ?