POLR1B and ZNF207

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		POLR1B	ZNF207
Description		RNA polymerase I subunit B	zinc finger protein 207
Image			No pdb structure
GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Fibrillar Center Nucleus Nucleoplasm Chromosome Nucleolus RNA Polymerase I Complex Cytosol	Chromosome, Centromeric Region Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Spindle Cytoskeleton Microtubule Spindle Matrix
	Molecular Function	DNA Binding DNA-directed RNA Polymerase Activity Protein Binding Zinc Ion Binding Transferase Activity Nucleotidyltransferase Activity Ribonucleoside Binding 5'-3' RNA Polymerase Activity Metal Ion Binding DNA/RNA Hybrid Binding	DNA Binding RNA Binding Protein Binding Microtubule Binding Heparin Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	DNA-templated Transcription Embryo Implantation RRNA Transcription Neural Crest Formation Nucleologenesis	Mitotic Sister Chromatid Segregation Microtubule Bundle Formation Chromosome Segregation Mitotic Spindle Assembly Checkpoint Signaling Attachment Of Spindle Microtubules To Kinetochore Microtubule Polymerization Protein Stabilization Cell Division Regulation Of Chromosome Segregation Mitotic Spindle Assembly
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS			Survival in pancreatic cancer ( 28470677)
Interacting Genes		14 interacting genes: AKT2 CCND1 EIF3L ESR1 GIT2 HDAC6 LDB1 LZTR1 MED20 NFKBIB POLR1E RPL37 RRN3 ZNF207	10 interacting genes: CEBPA ERBB3 HNRNPM HNRNPUL1 MAP2K2 OGT POLR1B TET2 WBP4 WDR77
Entrez ID		84172	7756
HPRD ID		06852	04576
Ensembl ID		ENSG00000125630	ENSG00000010244
Uniprot IDs		B7Z1W6 Q9H9Y6	O43670
PDB IDs		7OB9 7OBA 7OBB 7VBA 7VBB 7VBC 8A43
Enriched GO Terms of Interacting Partners?		Macromolecule Biosynthetic Process Transcription Preinitiation Complex Assembly Nucleoplasm DNA-templated Transcription Protein-DNA Complex Assembly Transcription Initiation At RNA Polymerase I Promoter RNA Polymerase I Preinitiation Complex Assembly Nucleobase-containing Compound Biosynthetic Process Regulation Of Intracellular Signal Transduction Protein-containing Complex Organization Mammary Gland Epithelial Cell Proliferation Response To Corticosterone Mammary Gland Alveolus Development Macromolecule Metabolic Process Cellular Component Assembly Enzyme Binding Protein-containing Complex Protein-containing Complex Assembly Response To Mineralocorticoid RNA Metabolic Process Fibroblast Proliferation Cellular Response To High Light Intensity RNA Polymerase II Preinitiation Complex Assembly Transcription Corepressor Binding Spindle Matrix Polyubiquitinated Misfolded Protein Transport Positive Regulation Of Cholangiocyte Proliferation RNA Polymerase I General Transcription Initiation Factor Binding Positive Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of Signal Transduction Cell Leading Edge Response To High Light Intensity Response To Hormone Retinal Rod Cell Apoptotic Process Cyclin D1-CDK4 Complex Cyclin D1-CDK6 Complex Response To Estrogen Transcription By RNA Polymerase II Transcription Coactivator Activity Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Cellular Response To Oxidative Stress Acetylspermidine Deacetylase Activity Polyamine Deacetylation Spermidine Deacetylation Peroxidase Inhibitor Activity Negative Regulation Of Aggrephagy Tubulin Deacetylase Activity DNA-templated Transcription Initiation Cellular Response To Hormone Stimulus Positive Regulation Of Cap-dependent Translational Initiation	ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Positive Regulation Of Gene Expression Schwann Cell Development Macromolecule Metabolic Process ERBB2 Signaling Pathway Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Nucleoplasm RNA Splicing, Via Transesterification Reactions Cellular Developmental Process RNA Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Glial Cell Development Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Oocyte Axis Specification Positive Regulation Of Biosynthetic Process Chromatin DNA Binding CHOP-C/EBP Complex Positive Regulation Of RNA Biosynthetic Process Nucleus Cell Development Positive Regulation Of DNA-templated Transcription Response To Vitamin B2 Positive Regulation Of Macromolecule Biosynthetic Process C/EBP Complex Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Neuregulin Receptor Activity ERBB Signaling Pathway Myelination Axon Ensheathment MRNA Processing RNA Splicing Protein O-acetylglucosaminyltransferase Activity DNA 5-methylcytosine Dioxygenase Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Ribonucleoside Binding Nucleologenesis Protein O-linked Glycosylation Positive Regulation Of RNA Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nuclear Matrix White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?