TOLLIP and GGA1

Number of citations of the paper that reports this interaction (PubMedID 15047686)
0

Data Source:
BioGRID (pull down)

		TOLLIP	GGA1
Description		toll interacting protein	golgi associated, gamma adaptin ear containing, ARF binding protein 1
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Endosome Early Endosome Cytosol Nuclear Body Extrinsic Component Of Plasma Membrane Protein-containing Complex Azurophil Granule Lumen Specific Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleoplasm Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex
	Molecular Function	Interleukin-1, Type I Receptor Binding Protein Binding Kinase Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding SUMO Binding Toll-like Receptor Binding Ubiquitin Binding Molecular Adaptor Activity	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Immune System Process Ubiquitin-dependent Protein Catabolic Process Autophagy Inflammatory Response Signal Transduction Phosphorylation Epithelial Cell Differentiation Positive Regulation Of Protein Sumoylation Protein Localization To Endosome Innate Immune Response Leukocyte Activation Interleukin-1-mediated Signaling Pathway	Intracellular Protein Transport Golgi To Plasma Membrane Transport Intracellular Protein Localization Protein Transport Vesicle-mediated Transport Protein Catabolic Process Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Catabolic Process Protein Localization To Ciliary Membrane
Pathways		Neutrophil degranulation Interleukin-1 signaling	TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Gout ( 32238385) Idiopathic pulmonary fibrosis ( 24429156)	Health literacy ( 31250787)
Interacting Genes		78 interacting genes: ACTMAP ACTN2 ARRDC3 ATXN1 BHLHE40 CDIP1 CHD6 CIMIP2B CPSF6 CSN1S1 CSN2 DAB1 DAZAP2 DCDC2 DDIT4L DZIP3 FAM168A FTH1 GGA1 GGA2 GGA3 GUCD1 HERPUD1 IL1R1 IL1RAP IRAK1 IRAK2 KRTAP13-3 KRTAP15-1 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP7-1 LDB1 MEDAG MSS51 MSX2 MVP N4BP2 NEDD8 NRF1 NTAQ1 ODAM PEG10 PHAF1 PRPF39 PRR20A PRR20B PRR20C PRR20D PRR20E PSMB1 RBFOX1 RBFOX2 RBPMS RHOXF2 RNF167 RNF26 RSPH1 RUNX1 SEPTIN1 SETDB1 SIAH1 STN1 TBX3 TENT5A TLR2 TLR4 TOM1 TOM1L1 TTC9C USP54 WBP2 WRNIP1 XRN2 ZBTB16 ZHX1 ZMYND19	48 interacting genes: ADRA2B AFTPH AP1AR AP1G1 APP ARF1 ARF3 ARF5 ATXN7L1 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CFTR CLINT1 CLTC CSNK2A1 DGCR6L DTNB EGFR ETS1 F8 GGA2 GGA3 GTPBP4 GTSE1 IGF2R ING5 JUN LRP3 M6PR NPM1 RABEP1 RABGEF1 RNF11 RPS27A SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TP53 TSG101 UBC VPS18
Entrez ID		54472	26088
HPRD ID		05887	12078
Ensembl ID		ENSG00000078902	ENSG00000100083
Uniprot IDs		B3KR28 E9PNS3 F2Z2Y8 Q6FIE9 Q8N8J5 Q9H0E2	Q9UJY5
PDB IDs		1WGL 2N31	1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?		NAD+ Nucleosidase Activity, Cyclic ADP-ribose Generating Interleukin-1-mediated Signaling Pathway Endosome Membrane Ubiquitin Binding Positive Regulation Of Cellular Response To Macrophage Colony-stimulating Factor Stimulus Golgi To Plasma Membrane Protein Transport Lipopolysaccharide-mediated Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Positive Regulation Of Matrix Metallopeptidase Secretion Protein Binding Toll-like Receptor Signaling Pathway Intermediate Filament Cell Surface Pattern Recognition Receptor Signaling Pathway Establishment Of Protein Localization To Plasma Membrane Phosphatidylinositol Binding Golgi To Plasma Membrane Transport Interleukin-1 Receptor Activity Toll-like Receptor 2 Signaling Pathway Embryonic Hindlimb Morphogenesis Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Protein Localization To Cell Surface LIM Domain Binding Toll Signaling Pathway Lipopolysaccharide Immune Receptor Activity Interleukin-33-mediated Signaling Pathway Hindlimb Morphogenesis Forelimb Morphogenesis Identical Protein Binding	Early Endosome Endosome Protein Transport Establishment Of Protein Localization Intracellular Protein Transport Vesicle-mediated Transport Intracellular Transport Cellular Localization Endosome Membrane Vacuolar Transport Establishment Of Localization In Cell Clathrin-coated Vesicle Lysosomal Transport Intracellular Protein Localization Trans-Golgi Network Recycling Endosome Endocytosis Golgi Apparatus Early Endosome Membrane Import Into Cell Post-Golgi Vesicle-mediated Transport Establishment Of Protein Localization To Vacuole Perinuclear Region Of Cytoplasm Golgi Vesicle Transport Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Protein Localization To Vacuole Protein Targeting To Vacuole Positive Regulation Of MiRNA Transcription Receptor-mediated Endocytosis Negative Regulation Of Protein Metabolic Process Trans-Golgi Network Membrane Positive Regulation Of MiRNA Metabolic Process Protein Localization To Organelle Clathrin-coated Endocytic Vesicle Membrane Protein Targeting To Lysosome Enzyme Binding Regulation Of Cell Growth Clathrin-coated Pit Ubiquitin Protein Ligase Binding Retromer Complex Binding Regulation Of Vesicle-mediated Transport Golgi To Lysosome Transport Nuclear Envelope Lumen AP-1 Adaptor Complex Establishment Of Protein Localization To Organelle Late Endosome Regulation Of Cell Cycle Regulation Of Growth Protein-containing Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?