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SEPT4 and SNCB
Number of citations of the paper that reports this interaction (PMID
12695511
)
21
Data Source:
HPRD
(in vivo, in vitro)
SEPT4
SNCB
Gene Name
septin 4
synuclein, beta
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Mitochondrion
Cytoskeleton
Sperm Annulus
Nucleoplasm
Cytoplasm
Mitochondrion
Golgi Apparatus
Inclusion Body
Growth Cone
Neuronal Cell Body
Terminal Bouton
Molecular Function
GTPase Activity
Structural Molecule Activity
Protein Binding
GTP Binding
Phospholipase Inhibitor Activity
Calcium Ion Binding
Alpha-tubulin Binding
Beta-tubulin Binding
Biological Process
Apoptotic Process
Cell Cycle
Brain Development
Metabolic Process
Sperm Mitochondrion Organization
Positive Regulation Of Protein Ubiquitination
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Sperm Capacitation
Cell Division
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Synaptic Transmission
Dopamine Metabolic Process
Negative Regulation Of Catalytic Activity
Negative Regulation Of Neuron Apoptotic Process
Synapse Organization
Pathways
Drugs
Diseases
GWAS
Testicular germ cell tumor (
23666239
)
Protein-Protein Interactions
9 interactors:
AREL1
PARK2
SEPT5
SEPT8
SNCA
SNCAIP
SNCB
UBC
XIAP
11 interactors:
APP
CENPT
GRK1
GRK5
GRK6
HSPA1A
LNX1
PLK1
PLK3
SEPT4
SNCA
Entrez ID
5414
6620
HPRD ID
04738
03980
Ensembl ID
ENSG00000108387
ENSG00000074317
Uniprot IDs
O43236
G4Y815
G4Y816
Q16143
PDB IDs
Enriched GO Terms of Interacting Partners
?
Dopamine Metabolic Process
Catecholamine Metabolic Process
Regulation Of Neurotransmitter Secretion
Phenol-containing Compound Metabolic Process
Positive Regulation Of Protein Linear Polyubiquitination
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Cell Death
Regulation Of Synaptic Vesicle Transport
Regulation Of Synaptic Transmission
Regulation Of Apoptotic Process
Negative Regulation Of Catalytic Activity
Regulation Of Cell Death
Dopamine Transport
Neurotransmitter Uptake
Synaptic Transmission, Dopaminergic
Positive Regulation Of Protein Ubiquitination
Regulation Of Neurotransmitter Levels
Regulation Of Dopamine Secretion
Neurotransmitter Transport
Negative Regulation Of Neuron Apoptotic Process
Protein Ubiquitination
Monoamine Transport
Synaptic Transmission
Cellular Response To Catecholamine Stimulus
Protein Modification By Small Protein Conjugation
Regulation Of Protein Ubiquitination
Negative Regulation Of Neuron Death
Regulation Of Secretion
Regulation Of Proteolysis
Regulation Of Neuron Apoptotic Process
Regulation Of Neuron Death
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Proteolysis
Regulation Of Cellular Response To Oxidative Stress
Negative Regulation Of Protein Metabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Modification Process
Cell-cell Signaling
Neuron-neuron Synaptic Transmission
Regulation Of Signaling
Apoptotic Process
Regulation Of Vesicle-mediated Transport
Ammonium Transport
Programmed Cell Death
Regulation Of Cellular Localization
Negative Regulation Of Thrombin Receptor Signaling Pathway
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Hydrogen Peroxide Catabolic Process
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Cell Death
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Death
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Phosphorylation
Positive Regulation Of Proteolysis
Protein Phosphorylation
Response To Oxidative Stress
Regulation Of Protein Stability
Posttranscriptional Regulation Of Gene Expression
Apoptotic Process
Programmed Cell Death
Protein Destabilization
Cell Death
Death
Regulation Of Signal Transduction
Protein Metabolic Process
Negative Regulation Of Signal Transduction
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Ubiquitination
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Signaling
Cellular Protein Metabolic Process
Regulation Of Signaling
Positive Regulation Of Protein Metabolic Process
Cellular Protein Modification Process
Regulation Of Proteolysis
Regulation Of Protein Metabolic Process
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Proteolysis
Negative Regulation Of Thrombin Receptor Signaling Pathway
Positive Regulation Of Hydrogen Peroxide Catabolic Process
Positive Regulation Of Glutathione Peroxidase Activity
Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Norepinephrine Uptake
Positive Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Protein Processing
Regulation Of Cellular Amino Acid Metabolic Process
Regulation Of Protein Processing
Tagcloud
?
atp13a2
correction
dj1
genotyped
hapmap
htra2
individually
loci
lrrk1
lrrk2
mapt
midwest
omi
outbred
park
park2
pd
pink1
rs2435200
siblings
snca
sncg
snps
spr
tag
uchl1
uncorrected
usa
variants
Tagcloud (Difference)
?
atp13a2
correction
dj1
genotyped
hapmap
htra2
individually
loci
lrrk1
lrrk2
mapt
midwest
omi
outbred
park
park2
pd
pink1
rs2435200
siblings
snca
sncg
snps
spr
tag
uchl1
uncorrected
usa
variants
Tagcloud (Intersection)
?