SNCB and MORN4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNCB	MORN4
Description		synuclein beta	MORN repeat containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Inclusion Body Neuronal Cell Body Axon Terminus Synapse	Cytoplasm Stereocilium Stereocilium Tip Filopodium Tip Cell Projection Actin-based Cell Projection
	Molecular Function	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Transition Metal Ion Binding Cuprous Ion Binding	Protein Binding
	Biological Process	Chemical Synaptic Transmission Dopamine Metabolic Process Negative Regulation Of Neuron Apoptotic Process Synaptic Vesicle Endocytosis Synapse Organization Neuron Apoptotic Process	Response To Axon Injury
Pathways		MTF1 activates gene expression
Drugs
Diseases		Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)
GWAS			Bell's palsy ( 33602968)
Interacting Genes		13 interacting genes: AKT1 APP CENPT GRK1 GRK5 GRK6 HSPA1A LNX1 MORN4 PLK1 PLK3 SEPTIN4 SNCA	30 interacting genes: APOA5 BEND3 CRTAC1 DNAJC9 EXOSC8 F2RL1 GOPC GUCD1 HMMR INO80E KRT25 KRT27 MAGI2 NUTM1 NUTM2F NYAP2 PLAGL2 RHOQ SEPTIN11 SEPTIN6 SNCB SSX2IP SYTL2 TCF12 TCF4 TRIM23 TRIM44 WASHC1 WBP11 ZNF131
Entrez ID		6620	118812
HPRD ID		03980	16584
Ensembl ID		ENSG00000074317	ENSG00000171160
Uniprot IDs		G4Y815 G4Y816 Q16143	A6XB87 Q8NDC4
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Kinase Activity Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Protein Serine/threonine Kinase Activity Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Kinase Activity Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Catabolic Process Regulation Of Apoptotic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Programmed Cell Death Kinase Activity Beta-adrenergic Receptor Kinase Activity Protein Phosphorylation Regulation Of Proteolysis Phosphorylation Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Nucleotide Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Protein Localization Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Chaperone-mediated Autophagy ATP Binding Apoptotic Process Negative Regulation Of Apoptotic Process Postsynapse Phosphate-containing Compound Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Post-translational Protein Modification Programmed Cell Death Cell Death Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Regulation Of Signal Transduction Regulation Of Cell Cycle Inclusion Body Protein Autophosphorylation Transferase Activity Regulation Of Neurotransmitter Uptake Regulation Of Generation Of Precursor Metabolites And Energy Response To Oxidative Stress Cellular Response To Copper Ion Regulation Of Mitotic Spindle Assembly	Positive Regulation Of Pseudopodium Assembly Cell Division Site Septin Ring Septin Complex Golgi-associated Vesicle Membrane
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