SNCB and CENPT

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		SNCB	CENPT
Description		synuclein beta	centromere protein T
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Inclusion Body Neuronal Cell Body Axon Terminus Synapse	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body
	Molecular Function	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Transition Metal Ion Binding Cuprous Ion Binding	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Chemical Synaptic Transmission Dopamine Metabolic Process Negative Regulation Of Neuron Apoptotic Process Synaptic Vesicle Endocytosis Synapse Organization Neuron Apoptotic Process	Mitotic Cell Cycle Chromosome Segregation Chromosome Organization Cell Division Kinetochore Assembly
Pathways		MTF1 activates gene expression	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases		Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)
GWAS			Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		13 interacting genes: AKT1 APP CENPT GRK1 GRK5 GRK6 HSPA1A LNX1 MORN4 PLK1 PLK3 SEPTIN4 SNCA	8 interacting genes: APP CENPS COPS5 DHX29 H3C1 PPCDC SNCB TCEA2
Entrez ID		6620	80152
HPRD ID		03980	07811
Ensembl ID		ENSG00000074317	ENSG00000102901
Uniprot IDs		G4Y815 G4Y816 Q16143	B3KPB2 Q96BT3
PDB IDs			7QOO 7R5S 7XHN 7XHO 7YWX
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Kinase Activity Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Protein Serine/threonine Kinase Activity Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Kinase Activity Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Catabolic Process Regulation Of Apoptotic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Programmed Cell Death Kinase Activity Beta-adrenergic Receptor Kinase Activity Protein Phosphorylation Regulation Of Proteolysis Phosphorylation Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Nucleotide Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Protein Localization Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Chaperone-mediated Autophagy ATP Binding Apoptotic Process Negative Regulation Of Apoptotic Process Postsynapse Phosphate-containing Compound Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Post-translational Protein Modification Programmed Cell Death Cell Death Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Regulation Of Signal Transduction Regulation Of Cell Cycle Inclusion Body Protein Autophosphorylation Transferase Activity Regulation Of Neurotransmitter Uptake Regulation Of Generation Of Precursor Metabolites And Energy Response To Oxidative Stress Cellular Response To Copper Ion Regulation Of Mitotic Spindle Assembly	Transition Metal Ion Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Translation Initiation Factor Activity Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Protein Heterodimerization Activity Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Macrophage Migration Inhibitory Factor Binding Translational Initiation Nitric-oxide Synthase Complex
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