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SEPT4 and SEPT5
Number of citations of the paper that reports this interaction (PMID
15214843
)
8
Data Source:
HPRD
(two hybrid)
SEPT4
SEPT5
Gene Name
septin 4
septin 5
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Mitochondrion
Cytoskeleton
Sperm Annulus
Cytoskeleton
Plasma Membrane
Cell Cortex
Synaptic Vesicle
Terminal Bouton
Molecular Function
GTPase Activity
Structural Molecule Activity
Protein Binding
GTP Binding
GTPase Activity
Structural Molecule Activity
Protein Binding
GTP Binding
Biological Process
Apoptotic Process
Cell Cycle
Brain Development
Metabolic Process
Sperm Mitochondrion Organization
Positive Regulation Of Protein Ubiquitination
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Sperm Capacitation
Cell Division
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Cytokinesis
Metabolic Process
Synaptic Vesicle Targeting
Regulation Of Exocytosis
Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS
Testicular germ cell tumor (
23666239
)
DNA methylation (parent-of-origin) (
23725790
)
Protein-Protein Interactions
9 interactors:
AREL1
PARK2
SEPT5
SEPT8
SNCA
SNCAIP
SNCB
UBC
XIAP
18 interactors:
APP
KAT7
LSM8
MAGEA2B
MAPK6
MYOG
PARK2
PFN2
SEPT1
SEPT10
SEPT11
SEPT2
SEPT4
SEPT6
SEPT7
SEPT8
STX1A
STX4
Entrez ID
5414
5413
HPRD ID
04738
04100
Ensembl ID
ENSG00000108387
ENSG00000184702
Uniprot IDs
O43236
G3XAH0
Q99719
PDB IDs
Enriched GO Terms of Interacting Partners
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Dopamine Metabolic Process
Catecholamine Metabolic Process
Regulation Of Neurotransmitter Secretion
Phenol-containing Compound Metabolic Process
Positive Regulation Of Protein Linear Polyubiquitination
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Cell Death
Regulation Of Synaptic Vesicle Transport
Regulation Of Synaptic Transmission
Regulation Of Apoptotic Process
Negative Regulation Of Catalytic Activity
Regulation Of Cell Death
Dopamine Transport
Neurotransmitter Uptake
Synaptic Transmission, Dopaminergic
Positive Regulation Of Protein Ubiquitination
Regulation Of Neurotransmitter Levels
Regulation Of Dopamine Secretion
Neurotransmitter Transport
Negative Regulation Of Neuron Apoptotic Process
Protein Ubiquitination
Monoamine Transport
Synaptic Transmission
Cellular Response To Catecholamine Stimulus
Protein Modification By Small Protein Conjugation
Regulation Of Protein Ubiquitination
Negative Regulation Of Neuron Death
Regulation Of Secretion
Regulation Of Proteolysis
Regulation Of Neuron Apoptotic Process
Regulation Of Neuron Death
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Proteolysis
Regulation Of Cellular Response To Oxidative Stress
Negative Regulation Of Protein Metabolic Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Modification Process
Cell-cell Signaling
Neuron-neuron Synaptic Transmission
Regulation Of Signaling
Apoptotic Process
Regulation Of Vesicle-mediated Transport
Ammonium Transport
Programmed Cell Death
Regulation Of Cellular Localization
Negative Regulation Of Thrombin Receptor Signaling Pathway
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Hydrogen Peroxide Catabolic Process
Cell Cycle
Cell Division
Regulation Of Synaptic Vesicle Transport
Regulation Of Neurotransmitter Secretion
Synaptic Vesicle Fusion To Presynaptic Membrane
Regulation Of Synaptic Transmission
Positive Regulation Of Protein Ubiquitination
Regulation Of Vesicle-mediated Transport
Regulation Of Neurotransmitter Levels
Regulation Of Exocytosis
Neurotransmitter Transport
Regulation Of Synaptic Vesicle Exocytosis
Regulation Of Insulin Secretion
Regulation Of Protein Ubiquitination
Regulation Of Peptide Hormone Secretion
Vesicle Fusion
Synaptic Vesicle Exocytosis
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Muscle Atrophy
Positive Regulation Of Mitochondrial Fusion
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Hormone Secretion
Positive Regulation Of Exocytosis
Organelle Organization
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Secretion
Organelle Fusion
Sperm Mitochondrion Organization
Response To Muscle Activity Involved In Regulation Of Muscle Adaptation
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Eosinophil Degranulation
Positive Regulation Of Protein Linear Polyubiquitination
Regulation Of Embryonic Cell Shape
Positive Regulation Of Protein Metabolic Process
Vesicle Docking
Cellular Component Assembly
Exocytosis
Regulation Of Cellular Component Organization
Membrane Docking
Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Cellular Response To Dopamine
Dopamine Uptake Involved In Synaptic Transmission
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Localization
Regulation Of Protein Secretion
Cytokinesis
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Regulation Of L-glutamate Transport
Neurotransmitter Secretion
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