RBM11 and DCAF8

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		RBM11	DCAF8
Description		RNA binding motif protein 11	DDB1 and CUL4 associated factor 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cell Differentiation Cellular Response To Oxidative Stress	Myotube Cell Development Protein Ubiquitination
Pathways			Neddylation
Drugs
Diseases
GWAS			Breast size ( 27182965) Lung function (FEV1/FVC) ( 30061609) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		78 interacting genes: ACOT1 APP ATIC ATOSB ATRX BHLHE40 CEP85 CERCAM CHCHD3 CHD6 CNTNAP1 COPA CRYAB DALRD3 DAZAP2 DCAF8 DDX27 DDX6 DST DTX2 EDIL3 ENKD1 FN3K GABPB1 GADD45GIP1 GLIS2 GPATCH2L HERPUD2 HMG20A LRP1 MADD MAN1A2 MECOM MED13L METAP1 MYO15B NEFL NMT2 PCBP1 PCM1 PCYT1A PDHB PIBF1 PLCG1 PLEKHB1 POLG PRRC2A PSMD4 QKI RBFOX3 RHOXF2 RNF38 SAXO4 SCNM1 SCYL2 SF3B2 SNRNP70 SNRPA SNRPC SPRED1 STAMBP TUBB4A U2AF2 VIM ZCCHC8 ZFHX3 ZKSCAN5 ZMYND10 ZNF189 ZNF214 ZNF251 ZNF302 ZNF329 ZNF414 ZNF606 ZNF7 ZNF774 ZNF83	17 interacting genes: CRYAA DDB1 GSK3A GTPBP3 MDFI PIK3R3 PRMT1 PRMT8 RAF1 RBM11 RBPMS SPAST SUV39H1 THAP1 TNS2 TRIM54 WDR76
Entrez ID		54033	50717
HPRD ID		10185	18300
Ensembl ID		ENSG00000185272	ENSG00000132716
Uniprot IDs		P57052	B7Z8C9 Q5TAQ9
PDB IDs		2YWK	3I8E
Enriched GO Terms of Interacting Partners?		Nucleus RNA Splicing, Via Transesterification Reactions U1 SnRNA Binding MRNA Splicing, Via Spliceosome DNA Binding Spliceosomal Complex Zinc Ion Binding RNA Splicing Metal Ion Binding Nucleic Acid Binding U2-type Prespliceosome U1 SnRNP Regulation Of RNA Metabolic Process Astrocyte Activation Involved In Immune Response MRNA Binding MRNA Processing Commitment Complex Microtubule-based Process Stress Granule Assembly U1 SnRNP Binding	Epigenetic Programming Of Gene Expression Protein-arginine Omega-N Monomethyltransferase Activity Histone Methyltransferase Activity Peptidyl-arginine Methylation Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Protein-arginine N-methyltransferase Activity Methylation Insulin Receptor Signaling Pathway Epigenetic Programming In The Zygotic Pronuclei Identical Protein Binding Nucleus S-adenosyl-L-methionine Binding Macromolecule Methylation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Chromatin Remodeling Viral Protein Processing S-adenosylmethionine-dependent Methyltransferase Activity Viral Process Developmental Process Regulation Of Microtubule Cytoskeleton Organization Enzyme Binding Protein Methylation Methyltransferase Activity Regulation Of Microtubule Depolymerization Cellular Developmental Process Protein-containing Complex Assembly Negative Regulation Of UDP-glucose Catabolic Process Cell Differentiation Protein Homooligomerization GATOR1 Complex Binding Chromatin Organization Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Cellular Response To Insulin Stimulus RNA Processing Regulation Of Macromolecule Metabolic Process Heterochromatin Response To Stress Protein-containing Complex Organization Negative Regulation Of Signal Transduction Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Protein Complex Oligomerization Death-inducing Signaling Complex Assembly TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Regulation Of Microtubule-based Process Regulation Of Alternative MRNA Splicing, Via Spliceosome
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