RBM11 and SNRPA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBM11	SNRPA
Description		RNA binding motif protein 11	small nuclear ribonucleoprotein polypeptide A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP U4/U6 X U5 Tri-snRNP Complex Spliceosomal SnRNP Complex Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding Protein Homodimerization Activity	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding U1 SnRNA Binding Identical Protein Binding U1 SnRNP Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cell Differentiation Cellular Response To Oxidative Stress	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs			Malonic acid
Diseases
GWAS			Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) level) ( 27702941) Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio) ( 27702941) Caffeine metabolism (plasma 3,7-dimethylxanthine (theobromine) level) ( 27702941) Carotid intima media thickness (mean) ( 31801372) Hematocrit ( 27863252) melanoma-derived growth regulatory protein levels ( 25147954) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		78 interacting genes: ACOT1 APP ATIC ATOSB ATRX BHLHE40 CEP85 CERCAM CHCHD3 CHD6 CNTNAP1 COPA CRYAB DALRD3 DAZAP2 DCAF8 DDX27 DDX6 DST DTX2 EDIL3 ENKD1 FN3K GABPB1 GADD45GIP1 GLIS2 GPATCH2L HERPUD2 HMG20A LRP1 MADD MAN1A2 MECOM MED13L METAP1 MYO15B NEFL NMT2 PCBP1 PCM1 PCYT1A PDHB PIBF1 PLCG1 PLEKHB1 POLG PRRC2A PSMD4 QKI RBFOX3 RHOXF2 RNF38 SAXO4 SCNM1 SCYL2 SF3B2 SNRNP70 SNRPA SNRPC SPRED1 STAMBP TUBB4A U2AF2 VIM ZCCHC8 ZFHX3 ZKSCAN5 ZMYND10 ZNF189 ZNF214 ZNF251 ZNF302 ZNF329 ZNF414 ZNF606 ZNF7 ZNF774 ZNF83	84 interacting genes: ACAA2 APOBEC3C BAG4 CDKN2A CEBPA CFL1 CHTOP CIRBP CISD1 DAPK1 DAZAP1 DDIT4L DDX17 DDX39B DMRTB1 ENOX2 EXOSC8 FBXO7 FUBP1 GABPB1 HNRNPA0 HNRNPLL HNRNPR IL7R LENG8 LHX4 LNX1 LYAR MBNL1 MBNL2 METTL13 MRPL15 MTUS2 NDUFAF3 NXF1 OTX2 PAPOLA PCBP1 PCBP2 PCBP3 PEG10 PRPF6 PRR3 PTBP1 PTBP2 PUF60 QKI RASAL3 RBFOX2 RBM10 RBM11 RBM22 RBM3 RBM42 RBM4B RBM7 RBMX RBMY1A1 RBMY1F RBMY1J RBPMS2 RPL23 SDCBP SF1 SFPQ SMAD5 SNRPA1 SNRPN SRSF8 SUGP1 TFIP11 TIAL1 TLE5 TNFAIP8L1 TRIM27 TRIR U2AF2 UBC WBP4 YTHDF1 YTHDF3 ZC3H10 ZC3HAV1 ZCCHC13
Entrez ID		54033	6626
HPRD ID		10185	01658
Ensembl ID		ENSG00000185272	ENSG00000077312
Uniprot IDs		P57052	P09012
PDB IDs		2YWK	1AUD 1DRZ 1DZ5 1FHT 1M5K 1M5O 1M5P 1M5V 1NU4 1OIA 1SJ3 1SJ4 1SJF 1U6B 1URN 1VBX 1VBY 1VBZ 1VC0 1VC5 1VC6 1ZZN 2A3J 2NZ4 2OIH 2OJ3 2U1A 3BO2 3BO3 3BO4 3CUL 3CUN 3EGZ 3G8S 3G8T 3G96 3G9C 3HHN 3IIN 3IRW 3IWN 3K0J 3L3C 3MUM 3MUR 3MUT 3MUV 3MXH 3P49 3PGW 3R1H 3R1L 3UCU 3UCZ 3UD3 3UD4 4C4W 4PR6 4PRF 4W90 4W92 4YB1 5DDO 5DDP 5DDQ 5DDR 5FJ4 6LAS 6LAU 6LAX 6LAZ 6QX9 6SQN 6SQQ 6SQT 6SQV 6SR7 6XH0 6XH1 6XH2 6XH3 7AEP 7B0Y 7D7V 7DLZ 7DWH 7LHX 7QR3 7QR4 7VPX 8GXB 8GXC 8JY0
Enriched GO Terms of Interacting Partners?		Nucleus RNA Splicing, Via Transesterification Reactions U1 SnRNA Binding MRNA Splicing, Via Spliceosome DNA Binding Spliceosomal Complex Zinc Ion Binding RNA Splicing Metal Ion Binding Nucleic Acid Binding U2-type Prespliceosome U1 SnRNP Regulation Of RNA Metabolic Process Astrocyte Activation Involved In Immune Response MRNA Binding MRNA Processing Commitment Complex Microtubule-based Process Stress Granule Assembly U1 SnRNP Binding	RNA Binding Nucleic Acid Binding Regulation Of RNA Splicing MRNA Processing MRNA Metabolic Process RNA Splicing MRNA Binding Regulation Of MRNA Splicing, Via Spliceosome RNA Processing RNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Spliceosomal Complex Nucleic Acid Metabolic Process Nucleus MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleoplasm Positive Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Gene Expression Macromolecule Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of MRNA Metabolic Process Nuclear Speck Negative Regulation Of RNA Splicing Ribonucleoprotein Complex Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Cytoplasmic Stress Granule Protein Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Catalytic Step 2 Spliceosome Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process
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