RBM11 and CHD6

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		RBM11	CHD6
Description		RNA binding motif protein 11	chromodomain helicase DNA binding protein 6
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Chromatin Nucleus Nucleoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding Protein Homodimerization Activity	Nucleotide Binding Transcription Coregulator Binding DNA Binding Chromatin Binding ATP Binding ATP-dependent Activity, Acting On DNA Hydrolase Activity ATP Hydrolysis Activity Histone Binding ATP-dependent Chromatin Remodeler Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cell Differentiation Cellular Response To Oxidative Stress	Chromatin Organization Chromatin Remodeling Regulation Of Gene Expression Cell Redox Homeostasis Positive Regulation Of Transcription By RNA Polymerase II
Pathways			NFE2L2 regulating anti-oxidant/detoxification enzymes
Drugs
Diseases
GWAS			Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Appendicular lean mass ( 33097823) Diastolic blood pressure ( 27841878) Gastric adenocarcinoma (histologically verified) ( 26098866) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hippocampal atrophy ( 22745009) Low density lipoprotein cholesterol levels ( 32154731) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Refractive astigmatism ( 30306274) Systolic blood pressure ( 27841878) Total cholesterol levels ( 30275531) Triglyceride levels ( 32154731) Verbal declarative memory ( 25648963) Waist circumference ( 31170924)
Interacting Genes		78 interacting genes: ACOT1 APP ATIC ATOSB ATRX BHLHE40 CEP85 CERCAM CHCHD3 CHD6 CNTNAP1 COPA CRYAB DALRD3 DAZAP2 DCAF8 DDX27 DDX6 DST DTX2 EDIL3 ENKD1 FN3K GABPB1 GADD45GIP1 GLIS2 GPATCH2L HERPUD2 HMG20A LRP1 MADD MAN1A2 MECOM MED13L METAP1 MYO15B NEFL NMT2 PCBP1 PCM1 PCYT1A PDHB PIBF1 PLCG1 PLEKHB1 POLG PRRC2A PSMD4 QKI RBFOX3 RHOXF2 RNF38 SAXO4 SCNM1 SCYL2 SF3B2 SNRNP70 SNRPA SNRPC SPRED1 STAMBP TUBB4A U2AF2 VIM ZCCHC8 ZFHX3 ZKSCAN5 ZMYND10 ZNF189 ZNF214 ZNF251 ZNF302 ZNF329 ZNF414 ZNF606 ZNF7 ZNF774 ZNF83	7 interacting genes: ARAF ATXN1L H3-4 NFE2L2 RBM11 TOLLIP ZFYVE9
Entrez ID		54033	84181
HPRD ID		10185	13049
Ensembl ID		ENSG00000185272	ENSG00000124177
Uniprot IDs		P57052	Q8TD26
PDB IDs		2YWK	2EPB
Enriched GO Terms of Interacting Partners?		Nucleus RNA Splicing, Via Transesterification Reactions U1 SnRNA Binding MRNA Splicing, Via Spliceosome DNA Binding Spliceosomal Complex Zinc Ion Binding RNA Splicing Metal Ion Binding Nucleic Acid Binding U2-type Prespliceosome U1 SnRNP Regulation Of RNA Metabolic Process Astrocyte Activation Involved In Immune Response MRNA Binding MRNA Processing Commitment Complex Microtubule-based Process Stress Granule Assembly U1 SnRNP Binding
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