RBM11 and DST

Number of citations: 83 (PubMedID 35914814)
Data Source: BioGRID (two hybrid)

		RBM11	DST
Name		RNA binding motif protein 11	dystonin
Structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Stress Fiber Basement Membrane Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Microtubule Intermediate Filament Plasma Membrane Focal Adhesion Cell Cortex Basal Plasma Membrane Actin Cytoskeleton Microtubule Cytoskeleton Membrane Z Disc Hemidesmosome Axon Cell Leading Edge Cytoplasmic Vesicle H Zone Microtubule Plus-end Cell Projection Intermediate Filament Cytoskeleton Anchoring Junction Cell Periphery Polymeric Cytoskeletal Fiber Axon Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding Protein Homodimerization Activity	Actin Binding Integrin Binding Structural Molecule Activity Calcium Ion Binding Protein Binding Microtubule Binding Protein Homodimerization Activity Metal Ion Binding Microtubule Plus-end Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cell Differentiation Cellular Response To Oxidative Stress	Microtubule Cytoskeleton Organization Cytoskeleton Organization Cell Adhesion Integrin-mediated Signaling Pathway Retrograde Axonal Transport Response To Wounding Maintenance Of Cell Polarity Hemidesmosome Assembly Wound Healing Intermediate Filament Cytoskeleton Organization Cell Motility
Pathways		None	Type I hemidesmosome assembly RHOU GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
GWAS		No GWAS studies recorded	Alzheimer disease and age of onset ( 26830138 ) Appendicular lean mass ( 33097823 ) Attention function in attention deficit hyperactive disorder ( 26174813 ) Cerebrospinal fluid clusterin levels ( 26545630 ) Daytime sleep phenotypes ( 27126917 ) Gout (normal type) ( 32238385 ) Heel bone mineral density ( 30598549 ) Mean spheric corpuscular volume ( 32888494 ) Menarche (age at onset) ( 25231870 ) Red blood cell count ( 32888494 ) Small cell lung carcinoma ( 28604730 )
Novel Interactors		None recorded	1 novel interactors: BMP1
Interacting Genes		78 interacting genes: ACOT1 APP ATIC ATOSB ATRX BHLHE40 CEP85 CERCAM CHCHD3 CHD6 CNTNAP1 COPA CRYAB DALRD3 DAZAP2 DCAF8 DDX27 DDX6 DST DTX2 EDIL3 ENKD1 FN3K GABPB1 GADD45GIP1 GLIS2 GPATCH2L HERPUD2 HMG20A LRP1 MADD MAN1A2 MECOM MED13L METAP1 MYO15B NEFL NMT2 PCBP1 PCM1 PCYT1A PDHB PIBF1 PLCG1 PLEKHB1 POLG PRRC2A PSMD4 QKI RBFOX3 RHOXF2 RNF38 SAXO4 SCNM1 SCYL2 SF3B2 SNRNP70 SNRPA SNRPC SPRED1 STAMBP TUBB4A U2AF2 VIM ZCCHC8 ZFHX3 ZKSCAN5 ZMYND10 ZNF189 ZNF214 ZNF251 ZNF302 ZNF329 ZNF414 ZNF606 ZNF7 ZNF774 ZNF83	50 interacting genes: ABI1 ANKRD1 APC C1QTNF9 CALM1 CDC5L CELSR3 CEP63 CLIP4 COL17A1 DCTN1 DISC1 DSCAM DSCR9 DTNBP1 ECPAS EIF4ENIF1 ERBB2 ERBIN EXOC1 FTCD HUNK ITGB4 ITSN1 ITSN2 KIAA1549 KRT14 KRT5 LINC01554 MAPK6 MORC3 MTNR1B MYBPC2 NFYC NRIP1 PAK2 PCNT PRKAB2 PRKD2 PTGER4 RBM11 RSPH1 SH3BP5 SMAD9 SNAPIN TNIK TRAF3IP1 TTC3 TULP3 USP7
Entrez ID		54033	667
HPRD ID		10185	00222
Ensembl ID		ENSG00000185272	ENSG00000151914
Uniprot IDs		P57052	A0A7P0T890 B4DGY0 B4DSS9 E9PHM6 F6QMI7 F8W9J4 Q03001 Q6P0N6
PDB IDs		2YWK	3GJO 7OLG
GO Terms Enriched among Interactors		Nucleus RNA Splicing, Via Transesterification Reactions U1 SnRNA Binding MRNA Splicing, Via Spliceosome DNA Binding Spliceosomal Complex Zinc Ion Binding RNA Splicing Metal Ion Binding Nucleic Acid Binding U2-type Prespliceosome U1 SnRNP Regulation Of RNA Metabolic Process Astrocyte Activation Involved In Immune Response MRNA Binding MRNA Processing Commitment Complex Microtubule-based Process Stress Granule Assembly U1 SnRNP Binding	Signal Transduction Hemidesmosome Cytoskeleton Organization Intracellular Signal Transduction Clathrin-dependent Synaptic Vesicle Endocytosis Regulation Of Dendritic Spine Development Plasma Membrane Bounded Cell Projection Organization Cell Projection Organization Centrosome Developmental Process Cytosol Hemidesmosome Assembly Cytoplasm Vesicle-mediated Transport In Synapse Organelle Organization Molecular Adaptor Activity Anatomical Structure Morphogenesis Cytoskeleton Regulation Of Neuron Projection Development Ciliary Base Presynaptic Endocytosis Cellular Component Assembly Cell Junction Organization Dendrite Morphogenesis Cell Surface Receptor Signaling Pathway Protein Binding Microtubule-based Process Protein Phosphorylation Plasma Membrane Bounded Cell Projection Assembly Regulation Of Plasma Membrane Bounded Cell Projection Organization Titin Binding Nucleoplasm Cell Junction Assembly Regulation Of Cell Projection Organization Cell Projection Assembly Cell Leading Edge Cilium Assembly Axonal Transport Organelle Assembly Neuron Cellular Homeostasis Dendritic Spine Development Neuron Projection Morphogenesis Phosphorylation Basal Plasma Membrane Protein Tyrosine Kinase Activator Activity Embryonic Camera-type Eye Development Negative Regulation Of Interferon-beta Production Anterograde Synaptic Vesicle Transport BLOC-1 Complex Positive Regulation Of Cell Growth