RBM11 and CNTNAP1

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		RBM11	CNTNAP1
Description		RNA binding motif protein 11	contactin associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Membrane Paranodal Junction Paranode Region Of Axon Anchoring Junction Glutamatergic Synapse
	Molecular Function	Nucleic Acid Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(U) RNA Binding Protein Homodimerization Activity	Protein Binding SH3 Domain Binding Signaling Receptor Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Cell Differentiation Cellular Response To Oxidative Stress	Protein Localization To Paranode Region Of Axon Mitochondrion Organization Cytoskeleton Organization Cell Adhesion Signal Transduction Axonogenesis Central Nervous System Development Neuronal Action Potential Propagation Central Nervous System Myelination Myelination In Peripheral Nervous System Paranodal Junction Assembly Neuron Projection Development Myelination Neuron Projection Morphogenesis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance Neuromuscular Process Protein Localization To Juxtaparanode Region Of Axon Regulation Of Synapse Maturation Postsynaptic Density Organization Neuromuscular Junction Development, Skeletal Muscle Fiber Paranodal Junction Maintenance
Pathways			Neurofascin interactions
Drugs
Diseases
GWAS			Breast cancer ( 29059683) Major depressive disorder ( 27777418) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		78 interacting genes: ACOT1 APP ATIC ATOSB ATRX BHLHE40 CEP85 CERCAM CHCHD3 CHD6 CNTNAP1 COPA CRYAB DALRD3 DAZAP2 DCAF8 DDX27 DDX6 DST DTX2 EDIL3 ENKD1 FN3K GABPB1 GADD45GIP1 GLIS2 GPATCH2L HERPUD2 HMG20A LRP1 MADD MAN1A2 MECOM MED13L METAP1 MYO15B NEFL NMT2 PCBP1 PCM1 PCYT1A PDHB PIBF1 PLCG1 PLEKHB1 POLG PRRC2A PSMD4 QKI RBFOX3 RHOXF2 RNF38 SAXO4 SCNM1 SCYL2 SF3B2 SNRNP70 SNRPA SNRPC SPRED1 STAMBP TUBB4A U2AF2 VIM ZCCHC8 ZFHX3 ZKSCAN5 ZMYND10 ZNF189 ZNF214 ZNF251 ZNF302 ZNF329 ZNF414 ZNF606 ZNF7 ZNF774 ZNF83	9 interacting genes: CCR4 FYN LCOR NFASC PTPRB RBM11 RHOA RTN4 SRC
Entrez ID		54033	8506
HPRD ID		10185	03825
Ensembl ID		ENSG00000185272	ENSG00000108797
Uniprot IDs		P57052	P78357
PDB IDs		2YWK
Enriched GO Terms of Interacting Partners?		Nucleus RNA Splicing, Via Transesterification Reactions U1 SnRNA Binding MRNA Splicing, Via Spliceosome DNA Binding Spliceosomal Complex Zinc Ion Binding RNA Splicing Metal Ion Binding Nucleic Acid Binding U2-type Prespliceosome U1 SnRNP Regulation Of RNA Metabolic Process Astrocyte Activation Involved In Immune Response MRNA Binding MRNA Processing Commitment Complex Microtubule-based Process Stress Granule Assembly U1 SnRNP Binding	Cell Migration Cell Motility Positive Regulation Of Podosome Assembly Phospholipase Activator Activity Regulation Of Podosome Assembly Contractile Actin Filament Bundle Assembly Stress Fiber Assembly Neuron Migration Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Platelet-derived Growth Factor Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Stimulatory C-type Lectin Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Platelet-derived Growth Factor Phospholipase Binding Cellular Response To Lectin Ephrin Receptor Binding Glial Cell Migration Cerebral Cortex Cell Migration Negative Regulation Of Inflammatory Response To Antigenic Stimulus Cell Junction Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Oxidative Stress Fc-gamma Receptor Signaling Pathway Negative Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Telencephalon Cell Migration Regulation Of Cell Projection Organization Substrate Adhesion-dependent Cell Spreading Forebrain Cell Migration Regulation Of Reactive Oxygen Species Biosynthetic Process T Cell Costimulation Leukocyte Migration Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Cell Junction Assembly Positive Regulation Of T Cell Activation Ephrin Receptor Signaling Pathway Cellular Response To Chemical Stress Peptidyl-tyrosine Phosphorylation Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Synapse Organization Negative Regulation Of Cell-substrate Adhesion Cell Differentiation Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Ficolin-1-rich Granule Membrane Actin Filament Bundle Organization Actin Filament Bundle Assembly
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