DXO and XRN2

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DXO	XRN2
Gene Name		decapping exoribonuclease	5-3 exoribonuclease 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane	Nucleus Nucleolus Membrane Aggresome
	Molecular Function	Nucleotide Binding Magnesium Ion Binding MRNA Binding 5'-3' Exonuclease Activity RNA Pyrophosphohydrolase Activity	Transcription Termination Site Sequence-specific DNA Binding Nuclease Activity 5'-3' Exoribonuclease Activity Zinc Ion Binding 5'-3' Exonuclease Activity Poly(A) RNA Binding
	Biological Process	MRNA Catabolic Process Metabolic Process RNA Destabilization Nuclear MRNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis	DNA Catabolic Process, Exonucleolytic DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated RNA Processing MRNA Processing RNA Catabolic Process Spermatogenesis Cell Growth RNA Metabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways			Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: EXOSC10 EXOSC4 EXOSC7 FLOT2 PRMT6 UPF1 XRN1 XRN2	24 interactors: ALDH1B1 ATRN COMT CSNK2A1 CTSC DISC1 DXO EEF1A1 EIF3L EIF5A EIF6 ERG EXOSC10 EXOSC8 LSM3 MOCS3 MRPL4 MRPS10 PRAME PSMA3 TARDBP TIPARP TOLLIP UPF2
Entrez ID		1797	22803
HPRD ID		16186	10309
Ensembl ID		ENSG00000204348	ENSG00000088930
Uniprot IDs		O77932	Q9H0D6
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone MRNA Catabolic Process RNA Catabolic Process Histone MRNA Metabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Nuclear MRNA Surveillance MRNA Catabolic Process Aromatic Compound Catabolic Process RNA Surveillance MRNA Metabolic Process Nucleic Acid Phosphodiester Bond Hydrolysis RNA Phosphodiester Bond Hydrolysis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Cellular Macromolecule Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Dosage Compensation By Inactivation Of X Chromosome Catabolic Process Dosage Compensation RRNA Catabolic Process RNA Metabolic Process RRNA Processing Gene Expression NcRNA Metabolic Process Maturation Of 5.8S RRNA Ribosome Biogenesis Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Nitrogen Compound Metabolic Process DNA Metabolic Process Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Histone H3-R2 Methylation RNA Localization Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Regulation Of Gene Expression, Epigenetic DNA Deamination Intracellular MRNA Localization Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Translational Termination Histone H4-R3 Methylation Negative Regulation Of Amyloid Precursor Protein Catabolic Process Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation	Gene Expression Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Positive Regulation Of Protein Catabolic Process Aromatic Compound Catabolic Process MRNA Metabolic Process Nuclear MRNA Surveillance Translational Elongation RNA Surveillance Catabolic Process Regulation Of Protein Catabolic Process Translation Cellular Metabolic Process Translational Initiation RNA Metabolic Process Positive Regulation Of Protein Metabolic Process Cellular Macromolecule Catabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Nuclear Export Ribonucleoprotein Complex Biogenesis Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Cellular Macromolecule Biosynthetic Process Metabolic Process Estrogen Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Macromolecule Biosynthetic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process RNA Localization Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Wnt Signaling Pathway Ribosome Biogenesis Regulation Of Protein Metabolic Process Cellular Aromatic Compound Metabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Homocysteine Metabolic Process TRNA Wobble Position Uridine Thiolation Enzyme Active Site Formation Via L-cysteine Persulfide Cellular Response To Phosphate Starvation Negative Regulation Of Potassium Ion Export Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of RNA Stability Cellular Protein Metabolic Process Regulation Of Homocysteine Metabolic Process Protein Adenylylation Regulation Of Heart Rate By Hormone
Tagcloud ?		1beta bioreactor cd11b cdh5 constructs dataset dioxepan ec ecs engineered hif immunodeficient immunofluorescent implanted lactide leukocyte leukocytes lla migrating msc mscs multipotent pecam retrieved scaffolds subcutaneously toll transmigration umbilical	8s arabidopsis at1g52930 at3g15460 atbrx1 biogenesis brx1 bypassed ets eukaryotes export implying intermediates its1 leaves nucleolus orthologs plant pointed processing rbfs ribosomal ribosome rrna spacer steps thaliana transcribed ubiquitously
Tagcloud (Difference) ?		1beta bioreactor cd11b cdh5 constructs dataset dioxepan ec ecs engineered hif immunodeficient immunofluorescent implanted lactide leukocyte leukocytes lla migrating msc mscs multipotent pecam retrieved scaffolds subcutaneously toll transmigration umbilical	8s arabidopsis at1g52930 at3g15460 atbrx1 biogenesis brx1 bypassed ets eukaryotes export implying intermediates its1 leaves nucleolus orthologs plant pointed processing rbfs ribosomal ribosome rrna spacer steps thaliana transcribed ubiquitously
Tagcloud (Intersection) ?