PTOV1 and USP16

Number of citations of the paper that reports this interaction (PMID 21090589)
3

Data Source:
BioGRID (unspecified method)

		PTOV1	USP16
Gene Name		prostate tumor overexpressed 1	ubiquitin specific peptidase 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm
	Molecular Function		Transcription Coactivator Activity Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Zinc Ion Binding Histone Binding Ubiquitin Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Cell Cycle Mitotic Nuclear Division Histone Deubiquitination Monoubiquitinated Histone H2A Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Homotetramerization Cell Division Regulation Of Proteasomal Protein Catabolic Process Histone H2A K63-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: DMTN GNB2L1 HDAC6 PIN1 SPTAN1 TMCC2 UBC USP16	12 interactors: CALM1 CDK1 EXOSC10 FBXO11 HIST1H2AB HIST1H2BB HIST2H2AA3 HIST2H2AC HIST4H4 PTOV1 UBC UBD
Entrez ID		53635	10600
HPRD ID		17929	06881
Ensembl ID		ENSG00000104960	ENSG00000156256
Uniprot IDs		Q86YD1	Q9Y5T5
PDB IDs			2I50
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Complex Assembly Negative Regulation Of Protein Complex Disassembly Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Depolymerization Regulation Of Protein Metabolic Process Regulation Of Protein Complex Disassembly Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Cytoskeleton Organization Regulation Of Cell Motility Regulation Of Proteolysis Regulation Of Locomotion Regulation Of Cellular Component Movement Regulation Of Response To Reactive Oxygen Species Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Regulation Of Organelle Organization Negative Regulation Of Type I Interferon Production Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Response To Oxidative Stress Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Actin Filament Capping Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Protein Phosphorylation Negative Regulation Of Actin Filament Depolymerization Regulation Of Protein Catabolic Process Negative Regulation Of Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Ligase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation Negative Regulation Of Protein Polymerization Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Platelet Aggregation Hsp90 Deacetylation Ubiquitin-dependent Protein Catabolic Process Regulation Of Cytoskeleton Organization Modification-dependent Protein Catabolic Process Cell Cycle Regulation Of Signal Transduction	Cellular Macromolecule Catabolic Process Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process DNA Packaging Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Protein Catabolic Process Response To Amine Fc Receptor Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity DNA Conformation Change Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Glycogen Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle MyD88-independent Toll-like Receptor Signaling Pathway Innate Immune Response Toll-like Receptor 3 Signaling Pathway Pronuclear Fusion Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription MyD88-dependent Toll-like Receptor Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Polysaccharide Metabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Mitotic DNA Damage Checkpoint Vascular Endothelial Growth Factor Receptor Signaling Pathway Mitotic DNA Integrity Checkpoint Toll-like Receptor Signaling Pathway Immune Response-regulating Signaling Pathway
Tagcloud ?		acquired cbp coactivator consistently cooperates cytotoxicity determinants dissociation far forming impaired mediates nucleus obscure obstacle promoting ra rar remained repression responsive retinoic retinoids ternary thereby trans translocating widely zyxin	critically defective deubiquitinase deubiquitinates deubiquitination enter example h2a h2b hela hox identifies laevis ligase mitosis mitotic modifications notably nucleosomal owing posterior predominately prefers prerequisite segregation slow ubiquitination ubp xenopus
Tagcloud (Difference) ?		acquired cbp coactivator consistently cooperates cytotoxicity determinants dissociation far forming impaired mediates nucleus obscure obstacle promoting ra rar remained repression responsive retinoic retinoids ternary thereby trans translocating widely zyxin	critically defective deubiquitinase deubiquitinates deubiquitination enter example h2a h2b hela hox identifies laevis ligase mitosis mitotic modifications notably nucleosomal owing posterior predominately prefers prerequisite segregation slow ubiquitination ubp xenopus
Tagcloud (Intersection) ?