USP16 and LINC02381

Number of citations of the paper that reports this interaction (PubMedID 36197973)
50

Data Source:
BioGRID (unspecified method)

		USP16	LINC02381
Description		ubiquitin specific peptidase 16	long intergenic non-protein coding RNA 2381
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Transcription Coactivator Activity Cysteine-type Endopeptidase Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Zinc Ion Binding Hydrolase Activity Histone Binding Ribosomal Small Subunit Binding Ubiquitin Binding Metal Ion Binding Histone H2A Deubiquitinase Activity
	Biological Process	Mitotic Cell Cycle Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Proteolysis DNA Damage Response Regulation Of Gene Expression Protein Deubiquitination Monoubiquitinated Protein Deubiquitination Positive Regulation Of DNA-templated Transcription Positive Regulation Of Translational Elongation Positive Regulation Of Transcription By RNA Polymerase II Protein Homotetramerization Cell Division Regulation Of Cell Cycle Positive Regulation Of Ribosome Biogenesis Mitotic Nuclear Division
Pathways		Ub-specific processing proteases
Drugs
Diseases
GWAS
Interacting Genes		23 interacting genes: CALM1 CDK1 DNM1L EXOSC10 FAU FBXO11 H2AC18 H2AC20 H2AC4 H2AZ1 H2BC3 H4C16 ISG15 LINC02381 PAX6 PLK1 PTOV1 SATB1 TTK UBC UBD XRN2 ZEB2	1 interacting genes: USP16
Entrez ID		10600	400043
HPRD ID		06881
Ensembl ID		ENSG00000156256	ENSG00000250742
Uniprot IDs		Q9Y5T5
PDB IDs		2I50 8WG5
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Chromatin Nucleosome Protein Localization To Chromosome, Centromeric Region Protein Localization To Chromosome Chromatin Remodeling Protein Tag Activity Chromosome Regulation Of Chromosome Organization Chromatin Organization Post-translational Protein Modification Protein Ubiquitination Protein Localization To Organelle Ubiquitin Protein Ligase Binding Protein Modification By Small Protein Conjugation Protein Heterodimerization Activity Female Meiosis Chromosome Segregation Regulation Of Sister Chromatid Segregation Spindle Microtubule Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Metaphase/anaphase Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Involved In Mitosis Metaphase/anaphase Transition Of Cell Cycle Regulation Of Chromosome Segregation G2/M Transition Of Mitotic Cell Cycle Heterochromatin Formation Protein Localization To Chromatin Nucleoplasm Nucleus Mitotic Cell Cycle Phase Transition Cell Cycle G2/M Phase Transition Mitotic Nuclear Membrane Disassembly Proteolysis Involved In Protein Catabolic Process Cell Cycle Phase Transition Regulation Of Telomerase RNA Localization To Cajal Body Protein Localization To Kinetochore Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Meiotic Chromosome Segregation Nuclear Membrane Disassembly Negative Regulation Of Biosynthetic Process Membrane Disassembly Negative Regulation Of Chromosome Organization CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Metabolic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Negative Regulation Of Gene Expression Positive Regulation Of Protein Localization To Nucleus	Positive Regulation Of Ribosome Biogenesis Regulation Of Ribosome Biogenesis Positive Regulation Of Translational Elongation Mitotic Nuclear Division Histone H2A Deubiquitinase Activity Monoubiquitinated Protein Deubiquitination Regulation Of Translational Elongation Ribosomal Small Subunit Binding Protein Homotetramerization Cysteine-type Endopeptidase Activity Cysteine-type Deubiquitinase Activity Protein Deubiquitination Nuclear Division Ubiquitin Binding Protein Tetramerization Protein Modification By Small Protein Removal Cysteine-type Peptidase Activity Mitotic Cell Cycle Positive Regulation Of Translation Histone Binding Protein Homooligomerization
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