AQP8

Name	aquaporin 8
Structure	No pdb structure
Interactors	6 interactors: CYBC1 PLP2 PLPP6 SERP1 STX12 TMEM120B
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Endoplasmic Reticulum Smooth Endoplasmic Reticulum Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Smooth Endoplasmic Reticulum Membrane Brush Border Membrane Mitochondrial Membrane Apical Part Of Cell Intracellular Canaliculus Intracellular Vesicle
	Molecular Function	Protein Binding Ammonium Channel Activity Water Channel Activity Methylammonium Channel Activity Urea Channel Activity Channel Activity
	Biological Process	Water Transport Urea Transport Methylammonium Transport One-carbon Compound Transport B Cell Differentiation Transepithelial Water Transport Regulation Of Cholesterol Biosynthetic Process Transmembrane Transport Cellular Response To CAMP Urea Transmembrane Transport Ammonium Transmembrane Transport Methylammonium Transmembrane Transport Hydrogen Peroxide Transmembrane Transport Ammonium Import Across Plasma Membrane Cellular Detoxification
Pathways	Detoxification of Reactive Oxygen Species Passive transport by Aquaporins Developmental Lineage of Pancreatic Acinar Cells
GWAS	Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856 )
Entrez ID	343
HPRD ID	04778
Ensembl ID	ENSG00000103375
Uniprot IDs	O94778
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Endoplasmic Reticulum Membrane Nuclear Inner Membrane Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Endoplasmic Reticulum Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Chemokine Binding Postsynaptic Recycling Endosome Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion Respiratory Burst Involved In Defense Response Respiratory Burst After Phagocytosis Lipid Phosphatase Activity Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Protein Prenylation Lysophosphatidic Acid Phosphatase Activity Regulation Of Neutrophil Activation Monoatomic Ion Transmembrane Transporter Activity Membrane Regulation Of Growth Hormone Secretion Phosphatidate Phosphatase Activity