PFN1 and DNM2

  • Number of citations of the paper that reports this interaction (PMID 12419186)
  • 53
  • Data Source:
  • HPRD (in vivo, in vitro)

PFN1

DNM2

Gene Name profilin 1 dynamin 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 30 interactors: ACTA1 ACTB APBB1IP C14orf1 CMA1 CRMP1 DBN1 DLG5 DNM2 ENAH FMNL1 GPHN LRIF1 MLLT4 MYPOP NCK1 PIK3R1 RAD51 RHOQ SRPK1 STUB1 TLE1 UNC119 VASP VIPR1 WASF1 WASL WIPF2 XPO6 YWHAQ 52 interactors: AMPH AOC1 AP2A1 APP ATF7IP ATXN3 BIN1 CCDC90B CCR5 CCT7 CDK1 CTTN DDX39B DNM1 DYNC1I1 DYNLL1 EIF3L EPS15 FNBP1 FNBP1L GDF9 GRB2 HCK HMGB1 ITSN1 ITSN2 KDR MAN1B1 MANEA MPHOSPH6 MPP6 PDE6G PFN1 PPIB PSTPIP1 PTK2 RPS2 RWDD2B SH3GL2 SH3GLB1 SHANK1 SHANK2 SNX9 SPRY2 SRC TIAM2 TRIP10 TYK2 VAV1 WBP4 ZBTB16 ZFAND6
Entrez ID 5216 1785
HPRD ID 01452 03852
Ensembl ID ENSG00000108518 ENSG00000079805
Uniprot IDs P07737 P50570 Q8N1K8
PDB IDs 1AWI 1CF0 1CJF 1FIK 1FIL 1PFL 2PAV 2PBD 3CHW 2YS1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
a20t  adds  aggregation  als  amyotrophic  classic  dementia  demonstrating  displayed  e117g  fatal  frontotemporal  hallmark  heterogeneity  insoluble  lateral  meta  neurodegenerative  pathology  postmortem  profilin  published  q139l  rare  sclerosis  sequenced  tar  transfections  variant 
bcl11b  cadherin  discovered  druggable  exhibitedthe  fat1  fbxw7  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
Tagcloud (Difference) ?
a20t  adds  aggregation  als  amyotrophic  classic  dementia  demonstrating  displayed  e117g  fatal  frontotemporal  hallmark  heterogeneity  insoluble  lateral  meta  neurodegenerative  pathology  postmortem  profilin  published  q139l  rare  sclerosis  sequenced  tar  transfections  variant 
bcl11b  cadherin  discovered  druggable  exhibitedthe  fat1  fbxw7  frequencies  guide  harboured  herc1  jak  jak3  lymphoblastic  mll2  mutational  notch1  notch2  phf6  recurrent  regulators  reln  secretase  splicing  subclonal  unfavourable  warranted  wt1  zrsr2 
Tagcloud (Intersection) ?