PEX7 and PEX5

Number of citations of the paper that reports this interaction (PMID 11865044)
25

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo, in vitro)

		PEX7	PEX5
Gene Name		peroxisomal biogenesis factor 7	peroxisomal biogenesis factor 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex
	Molecular Function	Peroxisome Matrix Targeting Signal-2 Binding Enzyme Binding Protein Homodimerization Activity	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding
	Biological Process	Neuron Migration Endochondral Ossification Fatty Acid Beta-oxidation Peroxisome Organization Ether Lipid Biosynthetic Process Protein Import Into Peroxisome Matrix	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization
Pathways
Drugs
Diseases
GWAS			IgG glycosylation ( 23382691)
Protein-Protein Interactions		7 interactors: ACAT1 KDM1A PEX13 PEX14 PEX5 PHYH PRMT6	68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772
Entrez ID		5191	5830
HPRD ID		03454	02684
Ensembl ID		ENSG00000112357	ENSG00000139197
Uniprot IDs		O00628 Q6FGN1	B4DR50 B4E0T2 P50542
PDB IDs			1FCH 2C0L 2C0M 2J9Q 2W84 3R9A
Enriched GO Terms of Interacting Partners?		Protein Import Into Peroxisome Matrix, Docking Protein To Membrane Docking Protein Import Into Peroxisome Matrix Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Negative Regulation Of Protein Homotetramerization Lipid Modification Carboxylic Acid Catabolic Process Peroxisome Organization Protein Import Into Peroxisome Matrix, Translocation Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Negative Regulation Of Protein Homooligomerization Fatty Acid Alpha-oxidation Membrane Docking Negative Regulation Of Protein Oligomerization Cellular Lipid Catabolic Process Protein Import Regulation Of Protein Oligomerization Brain Development Lipid Catabolic Process Head Development Fatty Acid Metabolic Process Cellular Lipid Metabolic Process Central Nervous System Development Establishment Of Protein Localization To Organelle Carboxylic Acid Metabolic Process Negative Regulation Of Protein Binding Organic Acid Metabolic Process Protein Targeting Protein Oligomerization Forebrain Development Lipid Metabolic Process Cerebral Cortex Cell Migration Peroxisome Transport Along Microtubule Cholesterol Storage Protein Import Into Peroxisome Matrix, Substrate Release Regulation Of Primitive Erythrocyte Differentiation Protein Localization To Organelle Telencephalon Cell Migration Forebrain Cell Migration Negative Regulation Of Binding Monocarboxylic Acid Metabolic Process Oxidation-reduction Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Histone H3-R2 Methylation Microtubule-based Peroxisome Localization	Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process
Tagcloud ?		aat2 aptamer bacteriophage colocalization dci1 gpd1 importation mdh3 mpps ms2 nonperoxisomal npy1 organellar pcd1 pcs60 peroxisomal peroxisomes pex1 pex11 pex14 pex28 pex3 pex5 pex6 pex8 pox1 puf5 rbp rfp	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?		aat2 aptamer bacteriophage colocalization dci1 gpd1 importation mdh3 mpps ms2 nonperoxisomal npy1 organellar pcd1 pcs60 pex1 pex11 pex14 pex28 pex3 pex6 pex8 pox1 puf5 rbp rfp	behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisome pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?		peroxisomal peroxisomes pex5