PEX7 and PEX5L

Number of citations of the paper that reports this interaction (PubMedID 25538232)
38

Data Source:
BioGRID (two hybrid)

		PEX7	PEX5L
Description		peroxisomal biogenesis factor 7	peroxisomal biogenesis factor 5 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Cytosol	Cytoplasm Peroxisomal Membrane Cytosol Membrane Receptor Complex
	Molecular Function	Peroxisome Matrix Targeting Signal-2 Binding Protein Binding Enzyme Binding Protein Homodimerization Activity	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Small GTPase Binding
	Biological Process	Neuron Migration Endochondral Ossification Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Peroxisome Organization Ether Lipid Biosynthetic Process Protein Transport Protein Import Into Peroxisome Matrix	Protein Import Into Peroxisome Matrix, Docking
Pathways		Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Refsum disease; Heredopathia atactica polyneuritiformis Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)
GWAS		Caffeine consumption from coffee or tea ( 33287642) Caffeine consumption from tea ( 33287642) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494)	Bipolar disorder ( 31043756) Childhood body mass index ( 33045005) Glucose homeostasis traits ( 25524916) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Type 2 diabetes ( 21490949)
Interacting Genes		8 interacting genes: ACAT1 KDM1A PEX13 PEX14 PEX5 PEX5L PHYH PRMT6	3 interacting genes: HCN1 PEX7 RAF1
Entrez ID		5191	51555
HPRD ID		03454	11425
Ensembl ID		ENSG00000112357	ENSG00000114757
Uniprot IDs		A0A7I2V2J8 O00628 Q6FGN1	Q8IYB4
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Substrate Release Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Unfolding Peroxisomal Membrane Protein Import Into Peroxisome Matrix Fatty Acid Oxidation Fatty Acid Catabolic Process Lipid Oxidation Establishment Of Protein Localization To Peroxisome Peroxisomal Membrane Transport Peroxisome Matrix Targeting Signal-1 Binding Peroxisome Organization Receptor Recycling Peroxisome Intracellular Protein Transmembrane Transport Lipid Modification Peroxisomal Importomer Complex Peroxisome Targeting Sequence Binding Receptor Metabolic Process Protein Monoubiquitination Carboxylic Acid Catabolic Process Fatty Acid Alpha-oxidation Lipid Catabolic Process Protein Transmembrane Transport Fatty Acid Metabolic Process Cellular Response To Reactive Oxygen Species Small Molecule Metabolic Process Protein-containing Complex Disassembly Monocarboxylic Acid Metabolic Process Response To Reactive Oxygen Species Protein Transmembrane Transporter Activity Cerebral Cortex Cell Migration Cellular Response To Oxidative Stress Telencephalon Cell Migration Forebrain Cell Migration Carboxylic Acid Metabolic Process Cellular Response To Chemical Stress Peroxisomal Matrix Organic Acid Metabolic Process Fatty Acid Beta-oxidation Metanephric Proximal Convoluted Tubule Development Propionyl-CoA Biosynthetic Process C-acetyltransferase Activity Peroxisome Transport Along Microtubule 2-oxobutyrate Catabolic Process Phytanoyl-CoA Dioxygenase Activity Lipid Localization Histone H2AR3 Methyltransferase Activity	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Intracellular Protein Localization Enzyme Binding Ether Lipid Biosynthetic Process Peroxisome Matrix Targeting Signal-2 Binding Type II Interferon-mediated Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Adenylate Cyclase Activator Activity ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Death-inducing Signaling Complex Assembly Neurotrophin TRK Receptor Signaling Pathway Pseudopodium Retinal Cone Cell Development Apical Dendrite Negative Regulation Of Synaptic Transmission, Glutamatergic Somatodendritic Compartment Negative Regulation Of Action Potential Regulation Of Membrane Hyperpolarization Voltage-gated Sodium Channel Activity Apical Protein Localization Intracellular CAMP-activated Cation Channel Activity Involved In Regulation Of Presynaptic Membrane Potential General Adaptation Syndrome, Behavioral Process Voltage-gated Monoatomic Cation Channel Activity HCN Channel Complex Regulation Of SA Node Cell Action Potential Intracellularly CAMP-activated Cation Channel Activity Maternal Behavior Parental Behavior Positive Regulation Of Membrane Hyperpolarization Establishment Of Protein Localization To Peroxisome Type B Pancreatic Cell Proliferation Schwann Cell Development Response To L-glutamate Ether Lipid Metabolic Process Peroxisomal Membrane Transport CAMP Binding Positive Regulation Of Peptidyl-serine Phosphorylation Face Development ERBB2 Signaling Pathway MAP Kinase Kinase Kinase Activity Endochondral Ossification Intracellular Protein Transmembrane Transport Peroxisome Organization Neurotrophin Signaling Pathway Regulation Of Peptidyl-serine Phosphorylation Response To Muscle Stretch Thyroid Gland Development Sodium Ion Import Across Plasma Membrane
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