GHRL and UBQLN1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GHRL	UBQLN1
Gene Name		ghrelin/obestatin prepropeptide	ubiquilin 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Axon Secretory Granule Lumen	Proteasome Complex Nucleoplasm Cytoplasm Endoplasmic Reticulum Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	G-protein Coupled Receptor Binding Growth Hormone-releasing Hormone Activity Protein Tyrosine Kinase Activator Activity Ghrelin Receptor Binding	Protein Binding Kinase Binding Protein Domain Specific Binding
	Biological Process	Activation Of MAPK Activity Gastric Acid Secretion Negative Regulation Of Endothelial Cell Proliferation Glucose Metabolic Process G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Actin Polymerization Or Depolymerization Adult Feeding Behavior Response To Hormone Hormone-mediated Signaling Pathway Dendrite Development Negative Regulation Of Angiogenesis Growth Hormone Secretion Positive Regulation Of Insulin Secretion Regulation Of Response To Food Positive Regulation Of Appetite Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Locomotion Positive Regulation Of Multicellular Organism Growth Regulation Of Cell Proliferation Negative Regulation Of Circadian Sleep/wake Cycle, REM Sleep Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Apoptotic Process Cortisol Secretion Response To Estrogen Cellular Protein Metabolic Process Negative Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Insulin Secretion Decidualization Negative Regulation Of Inflammatory Response Cartilage Development Positive Regulation Of Corticotropin Secretion Positive Regulation Of Cortisol Secretion Positive Regulation Of Synapse Assembly Regulation Of Excitatory Postsynaptic Membrane Potential Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation Of Protein Tyrosine Kinase Activity	Regulation Of Protein Ubiquitination Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ACE2 AGRP GHRHR GHSR LEP MLNR NPY UBQLN1	151 interactors: ABCC2 ACOT7 ADRM1 AGPAT5 AGR2 AGR3 APP ASCL1 ATXN3 BPIFA1 C1QA C1QTNF2 CALU CARKD CCL7 CCNB1 CD47 CD99 CD99L2 CHGB CHRNA3 CHRNA4 CHRNB4 COL10A1 COL1A2 COLGALT2 COMTD1 CSTF2 CSTF2T CTAG1B CTAG2 CYB5R1 DEFA6 DNAJB2 EFEMP2 EP300 EPS15 ERP27 ETNK1 F8 FAM127A FAM127B FAM127C FAM189A2 FAM86B3P FAS FBXO25 FCGR2A FGF7 FKBP2 FN1 FZD7 GABRA1 GABRA2 GABRA3 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GHRL GIT2 GKAP1 GPX3 GRM2 GYPB HERC3 HES1 HGS HK2 HSD17B12 HSPA13 IGL IGLC1 IGLV2-14 IL6ST IST1 ITPRIPL1 KLHL42 LITAF MANBAL MCM7 MIEF1 MIEF2 MLLT6 MTOR NBL1 NDE1 NGLY1 NME3 NPPA NPY NUPL1 P4HB PBXIP1 PIK3IP1 PLA2G16 PNMA1 PPIB PPIC PRAP1 PRB1 PRPF40A PSEN1 PSEN2 PSMD4 PSMD6 PTN RARA RASSF5 RIC8A RNF208 RPN1 RSRC2 SCG5 SCMH1 SERPINE1 SERPINI2 SIL1 SLC29A2 SMAD9 SMIM2 SMR3B SPARC SRGN STMN3 TARDBP TFF1 TICAM1 TMCO6 TMEM31 TMEM37 TMUB2 TNFRSF1A TNFRSF1B TREX1 TRIM32 TXNDC12 UBB UBC UBE2V1 UBQLN4 UBXN1 UBXN4 VCP XPO4 ZFAND2B ZG16 ZG16B ZMYM4 ZNF343
Entrez ID		51738	29979
HPRD ID		05638	05440
Ensembl ID		ENSG00000157017	ENSG00000135018
Uniprot IDs		Q9UBU3	Q9UMX0
PDB IDs		1P7X	2JY5 2JY6 2KLC
Enriched GO Terms of Interacting Partners?		Adult Feeding Behavior Feeding Behavior Regulation Of Response To Food Regulation Of Appetite Adult Behavior Behavior Female Pregnancy Positive Regulation Of Appetite Regulation Of Hormone Levels Peptide Hormone Secretion Peptide Secretion Response To Insulin Maternal Process Involved In Female Pregnancy Multicellular Organismal Reproductive Process Hormone Secretion Multicellular Organism Reproduction Hormone Transport Peptide Transport Growth Hormone Secretion Digestion Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Reproduction Single-organism Behavior Response To Peptide Hormone Amide Transport Response To Peptide G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Developmental Growth Regulation Of Blood Pressure Cellular Response To Hormone Stimulus Hormone Metabolic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Reproductive Process Regulation Of Peptide Hormone Secretion Eating Behavior Positive Regulation Of Growth Regulation Of Hormone Secretion Negative Regulation Of Peptide Secretion Response To Organonitrogen Compound Regulation Of Developmental Growth Cell Surface Receptor Signaling Pathway Blood Circulation Cell-cell Signaling Positive Regulation Of Multicellular Organism Growth Response To Hormone Regulation Of Vasoconstriction Negative Regulation Of Hormone Secretion Response To Stimulus Regulation Of Protein Metabolic Process Response To Nutrient Levels	Response To Stress Response To Organic Substance Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Response To Stimulus Regulation Of Protein Metabolic Process Cellular Response To Histamine Cellular Response To Organic Substance Cell-cell Signaling Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Synaptic Transmission Platelet Degranulation Signal Transduction Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Regulation Of ERBB Signaling Pathway Response To Histamine Chloride Transmembrane Transport Response To Organic Cyclic Compound Positive Regulation Of Protein Catabolic Process Signaling Cell Surface Receptor Signaling Pathway Response To Abiotic Stimulus Gamma-aminobutyric Acid Signaling Pathway Response To Hypoxia Cell Communication Chloride Transport Notch Signaling Pathway Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Immune System Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cellular Response To Oxygen Levels Regulation Of Cellular Process Defense Response Positive Regulation Of Cell Cycle Cellular Response To Ammonium Ion Notch Receptor Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud ?		breeding broiler bw bw49 bw70 bwg chickens desorption fcr feed fi flight genotyped ghrelin ghsr haplotypes igf1r maldi meanwhile rs14011776 rs14011780 rs14011783 rs14678932 rs14986828 rs15675065 rs15675067 rs16675844 snps yellow	affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose
Tagcloud (Difference) ?		breeding broiler bw bw49 bw70 bwg chickens desorption fcr feed fi flight genotyped ghrelin ghsr haplotypes igf1r maldi meanwhile rs14011776 rs14011780 rs14011783 rs14678932 rs14986828 rs15675065 rs15675067 rs16675844 snps yellow	affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose
Tagcloud (Intersection) ?