UBQLN1 and FZD7

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UBQLN1	FZD7
Gene Name		ubiquilin 1	frizzled class receptor 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Proteasome Complex Nucleoplasm Cytoplasm Endoplasmic Reticulum Protein Complex Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Kinase Binding Protein Domain Specific Binding	G-protein Coupled Receptor Activity Frizzled Binding Protein Binding Wnt-protein Binding PDZ Domain Binding Wnt-activated Receptor Activity
	Biological Process	Regulation Of Protein Ubiquitination Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Regulation Of Transcription, DNA-templated G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Cell-substrate Adhesion Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Stem Cell Maintenance Neuron Differentiation T Cell Differentiation In Thymus Substrate Adhesion-dependent Cell Spreading Regulation Of Catenin Import Into Nucleus Non-canonical Wnt Signaling Pathway Via JNK Cascade Positive Regulation Of Phosphorylation Negative Regulation Of Ectodermal Cell Fate Specification Positive Regulation Of Transcription, DNA-templated Positive Regulation Of JNK Cascade Somatic Stem Cell Division Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Canonical Wnt Signaling Pathway Mesenchymal To Epithelial Transition Cellular Response To Retinoic Acid
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Asymmetric localization of PCP proteins Signaling by Wnt Metabolic disorders of biological oxidation enzymes GPCR ligand binding PCP/CE pathway Class B/2 (Secretin family receptors) beta-catenin independent WNT signaling
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
Protein-Protein Interactions		151 interactors: ABCC2 ACOT7 ADRM1 AGPAT5 AGR2 AGR3 APP ASCL1 ATXN3 BPIFA1 C1QA C1QTNF2 CALU CARKD CCL7 CCNB1 CD47 CD99 CD99L2 CHGB CHRNA3 CHRNA4 CHRNB4 COL10A1 COL1A2 COLGALT2 COMTD1 CSTF2 CSTF2T CTAG1B CTAG2 CYB5R1 DEFA6 DNAJB2 EFEMP2 EP300 EPS15 ERP27 ETNK1 F8 FAM127A FAM127B FAM127C FAM189A2 FAM86B3P FAS FBXO25 FCGR2A FGF7 FKBP2 FN1 FZD7 GABRA1 GABRA2 GABRA3 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GHRL GIT2 GKAP1 GPX3 GRM2 GYPB HERC3 HES1 HGS HK2 HSD17B12 HSPA13 IGL IGLC1 IGLV2-14 IL6ST IST1 ITPRIPL1 KLHL42 LITAF MANBAL MCM7 MIEF1 MIEF2 MLLT6 MTOR NBL1 NDE1 NGLY1 NME3 NPPA NPY NUPL1 P4HB PBXIP1 PIK3IP1 PLA2G16 PNMA1 PPIB PPIC PRAP1 PRB1 PRPF40A PSEN1 PSEN2 PSMD4 PSMD6 PTN RARA RASSF5 RIC8A RNF208 RPN1 RSRC2 SCG5 SCMH1 SERPINE1 SERPINI2 SIL1 SLC29A2 SMAD9 SMIM2 SMR3B SPARC SRGN STMN3 TARDBP TFF1 TICAM1 TMCO6 TMEM31 TMEM37 TMUB2 TNFRSF1A TNFRSF1B TREX1 TRIM32 TXNDC12 UBB UBC UBE2V1 UBQLN4 UBXN1 UBXN4 VCP XPO4 ZFAND2B ZG16 ZG16B ZMYM4 ZNF343	6 interactors: DLG1 DLG2 DLG4 MAGI3 UBQLN1 UBQLN4
Entrez ID		29979	8324
HPRD ID		05440	04560
Ensembl ID		ENSG00000135018	ENSG00000155760
Uniprot IDs		Q9UMX0	O75084
PDB IDs		2JY5 2JY6 2KLC
Enriched GO Terms of Interacting Partners?		Response To Stress Response To Organic Substance Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Response To Stimulus Regulation Of Protein Metabolic Process Cellular Response To Histamine Cellular Response To Organic Substance Cell-cell Signaling Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Synaptic Transmission Platelet Degranulation Signal Transduction Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Regulation Of ERBB Signaling Pathway Response To Histamine Chloride Transmembrane Transport Response To Organic Cyclic Compound Positive Regulation Of Protein Catabolic Process Signaling Cell Surface Receptor Signaling Pathway Response To Abiotic Stimulus Gamma-aminobutyric Acid Signaling Pathway Response To Hypoxia Cell Communication Chloride Transport Notch Signaling Pathway Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Immune System Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cellular Response To Oxygen Levels Regulation Of Cellular Process Defense Response Positive Regulation Of Cell Cycle Cellular Response To Ammonium Ion Notch Receptor Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway	Receptor Localization To Synapse Nucleotide Phosphorylation Protein Localization To Synapse Receptor Clustering Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Cortical Actin Cytoskeleton Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Organophosphate Metabolic Process Protein Localization To Membrane Synaptic Transmission Regulation Of Intracellular Signal Transduction Phosphorylation Regulation Of Cellular Protein Metabolic Process Membrane Organization Establishment Or Maintenance Of Cell Polarity Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Cell-cell Signaling T Cell Cytokine Production Small Molecule Metabolic Process Regulation Of Catalytic Activity Hard Palate Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Regulation Of Membrane Potential Negative Regulation Of Receptor Internalization Regulation Of Signal Transduction Peristalsis Cytokine Production Involved In Immune Response Immunological Synapse Formation Locomotory Exploration Behavior Phosphate-containing Compound Metabolic Process Dendritic Spine Morphogenesis Synaptic Vesicle Maturation Maintenance Of Cell Polarity Cellular Protein Localization Regulation Of Signaling Vocalization Behavior Amyloid Precursor Protein Metabolic Process Axon Guidance Regulation Of Phosphorus Metabolic Process Membrane Raft Organization Dendritic Spine Development Endothelial Cell Proliferation Regulation Of Ion Transmembrane Transport Positive Regulation Of Catalytic Activity Negative Regulation Of Receptor-mediated Endocytosis
Tagcloud ?		affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose	199a 5p aberrant aberrantly biomarker called carcinogenesis elucidate fresh frizzled growing hcc hepatocarcinogenesis hepatocellular importantly indicates inversely jun mir mirnas perspective precise regulators restoration showing strengthened theoretical tumorigenesis wnt
Tagcloud (Difference) ?		affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose	199a 5p aberrant aberrantly biomarker called carcinogenesis elucidate fresh frizzled growing hcc hepatocarcinogenesis hepatocellular importantly indicates inversely jun mir mirnas perspective precise regulators restoration showing strengthened theoretical tumorigenesis wnt
Tagcloud (Intersection) ?