UBQLN1 and ABCC2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		UBQLN1	ABCC2
Gene Name		ubiquilin 1	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Proteasome Complex Nucleoplasm Cytoplasm Endoplasmic Reticulum Protein Complex Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Apical Plasma Membrane Intercellular Canaliculus
	Molecular Function	Protein Binding Kinase Binding Protein Domain Specific Binding	Protein Binding ATP Binding Organic Anion Transmembrane Transporter Activity Protein Domain Specific Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process	Regulation Of Protein Ubiquitination Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Transport Drug Transmembrane Transport Response To Oxidative Stress Metabolic Process Response To Heat Prostaglandin Transport Cellular Chloride Ion Homeostasis Response To Methotrexate Response To Estrogen Response To Arsenic-containing Substance Transmembrane Transport Thyroid Hormone Transport
Pathways			ABC-family proteins mediated transport
Drugs			Adenosine triphosphate Sulfinpyrazone
Diseases
GWAS
Protein-Protein Interactions		151 interactors: ABCC2 ACOT7 ADRM1 AGPAT5 AGR2 AGR3 APP ASCL1 ATXN3 BPIFA1 C1QA C1QTNF2 CALU CARKD CCL7 CCNB1 CD47 CD99 CD99L2 CHGB CHRNA3 CHRNA4 CHRNB4 COL10A1 COL1A2 COLGALT2 COMTD1 CSTF2 CSTF2T CTAG1B CTAG2 CYB5R1 DEFA6 DNAJB2 EFEMP2 EP300 EPS15 ERP27 ETNK1 F8 FAM127A FAM127B FAM127C FAM189A2 FAM86B3P FAS FBXO25 FCGR2A FGF7 FKBP2 FN1 FZD7 GABRA1 GABRA2 GABRA3 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GHRL GIT2 GKAP1 GPX3 GRM2 GYPB HERC3 HES1 HGS HK2 HSD17B12 HSPA13 IGL IGLC1 IGLV2-14 IL6ST IST1 ITPRIPL1 KLHL42 LITAF MANBAL MCM7 MIEF1 MIEF2 MLLT6 MTOR NBL1 NDE1 NGLY1 NME3 NPPA NPY NUPL1 P4HB PBXIP1 PIK3IP1 PLA2G16 PNMA1 PPIB PPIC PRAP1 PRB1 PRPF40A PSEN1 PSEN2 PSMD4 PSMD6 PTN RARA RASSF5 RIC8A RNF208 RPN1 RSRC2 SCG5 SCMH1 SERPINE1 SERPINI2 SIL1 SLC29A2 SMAD9 SMIM2 SMR3B SPARC SRGN STMN3 TARDBP TFF1 TICAM1 TMCO6 TMEM31 TMEM37 TMUB2 TNFRSF1A TNFRSF1B TREX1 TRIM32 TXNDC12 UBB UBC UBE2V1 UBQLN4 UBXN1 UBXN4 VCP XPO4 ZFAND2B ZG16 ZG16B ZMYM4 ZNF343	10 interactors: AZIN1 CANX MCPH1 NFKB1 PDZD3 PDZK1 RDX SHANK3 SLC9A3R1 UBQLN1
Entrez ID		29979	1244
HPRD ID		05440	03065
Ensembl ID		ENSG00000135018	ENSG00000023839
Uniprot IDs		Q9UMX0	Q92887
PDB IDs		2JY5 2JY6 2KLC
Enriched GO Terms of Interacting Partners?		Response To Stress Response To Organic Substance Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Response To Stimulus Regulation Of Protein Metabolic Process Cellular Response To Histamine Cellular Response To Organic Substance Cell-cell Signaling Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Synaptic Transmission Platelet Degranulation Signal Transduction Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Regulation Of ERBB Signaling Pathway Response To Histamine Chloride Transmembrane Transport Response To Organic Cyclic Compound Positive Regulation Of Protein Catabolic Process Signaling Cell Surface Receptor Signaling Pathway Response To Abiotic Stimulus Gamma-aminobutyric Acid Signaling Pathway Response To Hypoxia Cell Communication Chloride Transport Notch Signaling Pathway Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Immune System Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cellular Response To Oxygen Levels Regulation Of Cellular Process Defense Response Positive Regulation Of Cell Cycle Cellular Response To Ammonium Ion Notch Receptor Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway	Microvillus Assembly Microvillus Organization Protein Localization Renal Phosphate Ion Absorption Negative Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity Negative Regulation Of CGMP Biosynthetic Process Positive Regulation Of Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Striatal Medium Spiny Neuron Differentiation Negative Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Polyamine Transmembrane Transport Postsynaptic Density Assembly Guanylate Kinase-associated Protein Clustering Glutathione Transport Regulation Of Cytoskeleton Organization Negative Regulation Of Calcidiol 1-monooxygenase Activity Regulation Of Long Term Synaptic Depression Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of Cell Volume Positive Regulation Of Hyaluronan Biosynthetic Process Regulation Of Chromosome Condensation Positive Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Monocarboxylic Acid Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Catalytic Activity Cellular Protein Localization Regulation Of Transmembrane Transporter Activity Cellular Localization Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Ion Transport Negative Regulation Of Vitamin D Biosynthetic Process Renal Sodium Ion Transport N-methyl-D-aspartate Receptor Clustering Vocal Learning Positive Regulation Of Synapse Structural Plasticity Negative Regulation Of Cytoskeleton Organization Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of MiRNA Metabolic Process Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Transport Positive Regulation Of Ion Transport Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Positive Regulation Of Long-term Neuronal Synaptic Plasticity Phospholipase C-activating Dopamine Receptor Signaling Pathway Cellular Response To Nicotine Negative Regulation Of Catalytic Activity
Tagcloud ?		affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose	24c 24t 388g 521c abcc5 bjc bjcancer ces1 clarifying com diarrhoea doi glucuronide hampered irinotecan journal metabolising oatp oatp1b3 personalising pfs pharmacogenetic rs2244613 rs562 slco1b1 sn ugt1a1 www
Tagcloud (Difference) ?		affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose	24c 24t 388g 521c abcc5 bjc bjcancer ces1 clarifying com diarrhoea doi glucuronide hampered irinotecan journal metabolising oatp oatp1b3 personalising pfs pharmacogenetic rs2244613 rs562 slco1b1 sn ugt1a1 www
Tagcloud (Intersection) ?