UIMC1 and FANCG

Number of citations of the paper that reports this interaction (PMID 25132264)
0

Data Source:
BioGRID (fluorescent resonance energy transfer)

		UIMC1	FANCG
Gene Name		ubiquitin interaction motif containing 1	Fanconi anemia, complementation group G
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus BRCA1-A Complex	Nucleoplasm Nucleolus Cytoplasm Mitochondrion Plasma Membrane Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding Histone Binding Retinoid X Receptor Binding K63-linked Polyubiquitin Binding	Damaged DNA Binding Protein Binding
	Biological Process	Double-strand Break Repair Transcription, DNA-templated Response To Ionizing Radiation G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair Negative Regulation Of Transcription, DNA-templated Histone H2A K63-linked Deubiquitination	Cell Cycle Checkpoint Ovarian Follicle Development DNA Repair Mitochondrion Organization Spermatid Development Response To Radiation
Pathways			Fanconi Anemia pathway
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 22267201)
Protein-Protein Interactions		14 interactors: ATP8A2 BABAM1 BRCC3 CEP57 ESR1 FAM175A FANCG HIST2H2AC INO80B KIAA0368 MDC1 NR6A1 SKIL TP53	22 interactors: BRCA2 BRCC3 CAPN1 CDK1 CYP19A1 CYP2E1 ERCC4 FANCA FANCC FANCE FANCF FTSJ3 GABPB1 HES1 KRT19 PSMB1 RTN2 SAMD3 UIMC1 USHBP1 XRCC3 ZBED1
Entrez ID		51720	2189
HPRD ID		11482	04262
Ensembl ID		ENSG00000087206	ENSG00000221829
Uniprot IDs		Q96RL1	O15287 Q53XM5
PDB IDs		2RR9
Enriched GO Terms of Interacting Partners?		Cell Cycle Checkpoint Double-strand Break Repair DNA Repair DNA Damage Checkpoint Cell Cycle Process Positive Regulation Of Response To DNA Damage Stimulus Response To Radiation Cellular Response To DNA Damage Stimulus Cell Cycle Positive Regulation Of DNA Repair Regulation Of Response To DNA Damage Stimulus DNA Metabolic Process G2 DNA Damage Checkpoint Response To Ionizing Radiation Chromatin Organization Regulation Of DNA Repair Cellular Response To Stress Organelle Organization Chromosome Organization Chromatin Modification Response To Abiotic Stimulus Nucleobase-containing Compound Metabolic Process Protein K63-linked Deubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Multicellular Organismal Reproductive Process Positive Regulation Of DNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Multicellular Organism Reproduction Protein Import Into Nucleus, Translocation Cellular Response To Stimulus Response To Stimulus Transcription Initiation From RNA Polymerase II Promoter Response To X-ray Spermatogenesis Male Gamete Generation Nitrogen Compound Metabolic Process Reproduction DNA-templated Transcription, Initiation Single Organism Reproductive Process Gamete Generation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Antibiotic Reproductive Process Rhythmic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ovarian Follicle Development Sexual Reproduction Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process	Cellular Response To DNA Damage Stimulus DNA Repair DNA Metabolic Process Cellular Response To Stress Double-strand Break Repair Developmental Process Involved In Reproduction Heterocycle Metabolic Process Histone H2A K63-linked Deubiquitination Reproductive Structure Development Reproductive System Development Positive Regulation Of Mitotic Cell Cycle Single Organism Reproductive Process G2 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Response To Stress Cellular Nitrogen Compound Metabolic Process Reproductive Process DNA Damage Checkpoint Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Double-strand Break Repair Via Homologous Recombination Recombinational Repair Nucleotide-excision Repair Cell Cycle Cellular Response To Stimulus Protein K63-linked Deubiquitination Female Gonad Development Development Of Primary Female Sexual Characteristics Histone Deubiquitination Cellular Metabolic Process Reproduction Cell Cycle Process Response To Stimulus Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Histone Modification Response To X-ray Meiotic Nuclear Division Muscle Cell Development Positive Regulation Of DNA Repair Response To Radiation Response To Reactive Oxygen Species Meiotic Cell Cycle Regulation Of Cell Cycle Gonad Development Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Negative Regulation Of Stomach Neuroendocrine Cell Differentiation
Tagcloud ?			24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2
Tagcloud (Difference) ?			24h 300mum 513a 5p abp aminobiphenyl array arrays arylamine bioinformatic carcinogen comet damage deregulation eventually exo1 hepg2 lig1 mirna mirnas parallel pcna pcr qrt rad18 repair ung validated xrcc2
Tagcloud (Intersection) ?