UIMC1 and INO80B

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		UIMC1	INO80B
Gene Name		ubiquitin interaction motif containing 1	INO80 complex subunit B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus BRCA1-A Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Ino80 Complex
	Molecular Function	Protein Binding Histone Binding Retinoid X Receptor Binding K63-linked Polyubiquitin Binding	Protein Binding Metal Ion Binding
	Biological Process	Double-strand Break Repair Transcription, DNA-templated Response To Ionizing Radiation G2 DNA Damage Checkpoint Positive Regulation Of DNA Repair Negative Regulation Of Transcription, DNA-templated Histone H2A K63-linked Deubiquitination	DNA Repair DNA Recombination Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 22267201)
Protein-Protein Interactions		14 interactors: ATP8A2 BABAM1 BRCC3 CEP57 ESR1 FAM175A FANCG HIST2H2AC INO80B KIAA0368 MDC1 NR6A1 SKIL TP53	5 interactors: CD81 IGFBP2 PNMA1 SSX2IP UIMC1
Entrez ID		51720	83444
HPRD ID		11482	17110
Ensembl ID		ENSG00000087206	ENSG00000115274
Uniprot IDs		Q96RL1	Q9C086
PDB IDs		2RR9
Enriched GO Terms of Interacting Partners?		Cell Cycle Checkpoint Double-strand Break Repair DNA Repair DNA Damage Checkpoint Cell Cycle Process Positive Regulation Of Response To DNA Damage Stimulus Response To Radiation Cellular Response To DNA Damage Stimulus Cell Cycle Positive Regulation Of DNA Repair Regulation Of Response To DNA Damage Stimulus DNA Metabolic Process G2 DNA Damage Checkpoint Response To Ionizing Radiation Chromatin Organization Regulation Of DNA Repair Cellular Response To Stress Organelle Organization Chromosome Organization Chromatin Modification Response To Abiotic Stimulus Nucleobase-containing Compound Metabolic Process Protein K63-linked Deubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Multicellular Organismal Reproductive Process Positive Regulation Of DNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Multicellular Organism Reproduction Protein Import Into Nucleus, Translocation Cellular Response To Stimulus Response To Stimulus Transcription Initiation From RNA Polymerase II Promoter Response To X-ray Spermatogenesis Male Gamete Generation Nitrogen Compound Metabolic Process Reproduction DNA-templated Transcription, Initiation Single Organism Reproductive Process Gamete Generation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Antibiotic Reproductive Process Rhythmic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ovarian Follicle Development Sexual Reproduction Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process	Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Histone H2A K63-linked Deubiquitination Receptor-mediated Virion Attachment To Host Cell Intraciliary Transport Involved In Cilium Morphogenesis Virion Attachment To Host Cell Positive Regulation Of Cell Activation Adhesion Of Symbiont To Host Regulation Of Lymphocyte Activation Protein K63-linked Deubiquitination Regulation Of Cell Activation Histone Deubiquitination Positive Regulation Of Activated T Cell Proliferation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Tagcloud ?			2p13 absolutely consequence drastically eclampsia elucidation evolved founder genetics guided hemochorial icelandic linkage mer multifactorial paralogous pfam14465 placentally placentation pools premise prioritized pumillio rs34174194 trophoblast uguanaag utr uugucug winged
Tagcloud (Difference) ?			2p13 absolutely consequence drastically eclampsia elucidation evolved founder genetics guided hemochorial icelandic linkage mer multifactorial paralogous pfam14465 placentally placentation pools premise prioritized pumillio rs34174194 trophoblast uguanaag utr uugucug winged
Tagcloud (Intersection) ?