HOOK3 and AKTIP

Number of citations of the paper that reports this interaction (PMID 18799622)
9

Data Source:
HPRD (in vivo)

		HOOK3	AKTIP
Gene Name		hook microtubule-tethering protein 3	AKT interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Pericentriolar Material Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Microtubule Organizing Center Microtubule HOPS Complex Centriolar Satellite FHF Complex	Nucleolus Cytoplasm Golgi Apparatus Plasma Membrane HOPS Complex FHF Complex
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Early Endosome To Late Endosome Transport Negative Regulation Of Neurogenesis Golgi Localization Protein Localization To Centrosome Neuronal Stem Cell Maintenance	Positive Regulation Of Protein Phosphorylation Apoptotic Process Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Protein Ubiquitination Positive Regulation Of Protein Binding Early Endosome To Late Endosome Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: AKTIP HOOK1 HOOK2 VPS16 VPS41	23 interactors: AKT1 ASS1 C10orf2 CTBP2 DZIP3 EXOC7 FAM160A2 GTF3C1 HOOK1 HOOK2 HOOK3 IMMT KIAA1377 MARCH5 PDPK1 POLA2 RPA1 TRIM23 TRIM41 UTP14A VPS16 VPS18 VPS41
Entrez ID		84376	64400
HPRD ID		09699	07467
Ensembl ID		ENSG00000168172	ENSG00000166971
Uniprot IDs		Q86VS8	Q9H8T0
PDB IDs
Enriched GO Terms of Interacting Partners?		Vacuolar Transport Vacuole Organization Early Endosome To Late Endosome Transport Endosome To Lysosome Transport Endosome Organization Endosomal Transport Lysosomal Transport Lysosome Organization Protein Transport Regulation Of SNARE Complex Assembly Establishment Of Protein Localization Intracellular Transport Protein Localization Cytoplasmic Transport Establishment Of Localization In Cell Cellular Localization Regulation Of Vesicle Fusion Endomembrane System Organization Vesicle-mediated Transport Regulation Of Vacuole Fusion, Non-autophagic Vacuole Fusion, Non-autophagic Transport Organelle Organization Regulation Of Protein Complex Assembly Regulation Of Vesicle-mediated Transport Regulation Of Vacuole Organization Protein Targeting To Vacuole Establishment Of Protein Localization To Vacuole Viral Entry Into Host Cell Entry Into Host Cell Intracellular Protein Transport Regulation Of Organelle Organization Positive Regulation Of Protein Binding Organelle Fusion Interaction With Host	Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Protein Localization Organelle Organization Endosomal Transport Endomembrane System Organization Cytoplasmic Transport Cellular Localization Intracellular Transport Establishment Of Localization In Cell Regulation Of Vesicle Fusion Protein Localization To Organelle DNA-dependent DNA Replication Telomere Maintenance Via Semi-conservative Replication Protein Ubiquitination Cellular Protein Localization Nuclear DNA Replication Telomere Maintenance Via Recombination Protein Modification By Small Protein Conjugation Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Response To Epidermal Growth Factor Stimulus Vesicle-mediated Transport Positive Regulation Of Protein Localization To Plasma Membrane Response To Epidermal Growth Factor Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Protein Import Into Nucleus, Translocation Regulation Of Vesicle-mediated Transport DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening G1/S Transition Of Mitotic Cell Cycle Response To Fluid Shear Stress Cytoplasmic Microtubule Organization Viral Entry Into Host Cell Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Temperature Stimulus Viral Life Cycle Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Entry Into Host Cell Argininosuccinate Metabolic Process Regulation Of Vacuole Fusion, Non-autophagic
Tagcloud ?		akt1 akt2 aurka axon card11 deregulated exclusive exome fgfr2 grouping integrative massively men1 mlf1 mutually nets neuroendocrine nono pdgfr preponderance provisional recurrently si smad smad1 snvs therapeutically transitions vhl	apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works
Tagcloud (Difference) ?		akt1 akt2 aurka axon card11 deregulated exclusive exome fgfr2 grouping integrative massively men1 mlf1 mutually nets neuroendocrine nono pdgfr preponderance provisional recurrently si smad smad1 snvs therapeutically transitions vhl	apoa1bp apolipoprotein behaves biophysical cathepsin cellulo characterisation ctsb differently forkhead foxe3 implication initiating milieu modules mrnas naturally neighbouring pg4 qrt quadruplex quadruplexes recognises render scans though untranslated utr works
Tagcloud (Intersection) ?