TIMMDC1 and FAM210B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TIMMDC1	FAM210B
Description		translocase of inner mitochondrial membrane domain containing 1	family with sequence similarity 210 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane	Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitochondrial Respiratory Chain Complex I Assembly	Inflammatory Response Cell Differentiation Erythrocyte Differentiation Erythrocyte Maturation Skin Development Positive Regulation Of Erythrocyte Differentiation Spleen Development Cellular Response To Estradiol Stimulus Reactive Oxygen Species Metabolic Process
Pathways		Complex I biogenesis
Drugs
Diseases
GWAS		Autoimmune thyroid disease ( 32581359) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 24076602 31604244) Primary biliary cholangitis ( 30643196) Primary biliary cirrhosis ( 22961000) Systemic lupus erythematosus ( 28714469 33272962) Systemic sclerosis ( 31672989)
Interacting Genes		82 interacting genes: AGR3 ANKRD46 APOC2 APOC4 APOL2 APOL3 APP ARL6IP6 ARLN ATP6AP2 BCAP31 C14orf180 C3orf52 C5orf46 CCL4 CDS2 CMTM2 CREB3L1 CYB561D2 CYP4F12 DCBLD2 DIABLO DRAM1 EPGN FAM20B FAM210B FATE1 FXYD3 GJB2 GPR151 GPR152 GPX8 HGS HSD17B13 IFNA2 IGFBP5 KIR2DL4 LHFPL5 MARCHF5 NDUFB11 NINJ1 ORMDL1 ORMDL2 PEX16 PEX5 PIGF PTPN1 PTPRN REEP6 RNF24 SCAMP5 SCD SERF1A SERF1B SERP1 SERP2 SLC35E4 SLC35F6 SLC61A1 SLC71A2 SMO ST6GAL2 STX12 STX6 TMEM144 TMEM14B TMEM176A TMEM203 TMEM239 TMEM31 TMEM54 TMEM65 TMEM86A TVP23B UBIAD1 UNC50 UNC93A VAPB VMA12 YIF1A YIPF1 YIPF4	66 interacting genes: ADGRE2 APOL2 ATP6V0B ATP6V0C BCL2L13 BET1 C1GALT1 C5orf46 CCDC167 CD300C CLDND2 CNIH3 CYB5B CYB5R3 CYP4F2 EMP3 FIS1 FXYD6-FXYD2 GIMAP5 HEXB HMOX1 HMOX2 IER3IP1 IFITM3 INSIG2 LNPEP LPAR3 MFF MS4A13 NINJ2 NKG7 ORMDL2 OTOP3 PLP2 PLPP6 RPRM RTP2 SERP1 SERP2 SLC16A13 SLC30A8 SLC35B4 SLC35G1 SMCO4 SMIM1 STATH STX6 STX7 SYNJ2BP TF TFRC TIMM23 TIMMDC1 TMEM107 TMEM11 TMEM140 TMEM187 TMEM19 TMIE UBE2J1 VAMP1 VAMP3 VAMP4 VKORC1 YIF1A ZDHHC21
Entrez ID		51300	116151
HPRD ID		12817	12737
Ensembl ID		ENSG00000113845	ENSG00000124098
Uniprot IDs		C9JU35 Q9NPL8	Q96KR6
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Lipoprotein Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Golgi Membrane Response To Unfolded Protein Very-low-density Lipoprotein Particle Golgi Apparatus Response To Endoplasmic Reticulum Stress High-density Lipoprotein Particle Chemical Homeostasis Intermediate-density Lipoprotein Particle Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process Amyloid Fibril Formation Protein Import Into Peroxisome Membrane Negative Regulation Of Sphingolipid Biosynthetic Process Menaquinone Metabolic Process Synaptic Vesicle Membrane Serine Palmitoyltransferase Complex Endoplasmic Reticulum-Golgi Intermediate Compartment	Membrane Endoplasmic Reticulum Membrane SNARE Complex SNAP Receptor Activity Golgi Membrane Establishment Of Protein Localization Endoplasmic Reticulum Mitochondrial Outer Membrane Heme Oxidation Heme Oxygenase (decyclizing) Activity SNARE Complex Assembly Organelle Fusion Protein Binding Intracellular Chemical Homeostasis Nitric-oxide Synthase Complex Vesicle Fusion Synaptic Vesicle To Endosome Fusion Transport Vesicle Organelle Membrane Fusion Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Chemical Homeostasis Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Intracellular Monoatomic Cation Homeostasis Nitrite Reductase (NO-forming) Activity Multicellular Organismal-level Iron Ion Homeostasis Clathrin-coated Endocytic Vesicle Membrane Protein Targeting Multicellular Organismal-level Chemical Homeostasis Cellular Homeostasis Intracellular Monoatomic Ion Homeostasis Recycling Endosome Protein Targeting To Mitochondrion Nitric Oxide Metabolic Process Plasma Membrane Reactive Nitrogen Species Metabolic Process Membrane Fusion Cholesterol Biosynthetic Process HFE-transferrin Receptor Complex Negative Regulation Of Fatty Acid Transport Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain Proton-transporting V-type ATPase, V0 Domain Sterol Biosynthetic Process Bleb Assembly Heme Catabolic Process Response To Type II Interferon Golgi Vesicle Transport Azurophil Granule Protein Transport
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