FAM210B and OTOP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM210B	OTOP3
Description		family with sequence similarity 210 member B	otopetrin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Proton Channel Activity Identical Protein Binding
	Biological Process	Inflammatory Response Cell Differentiation Erythrocyte Differentiation Erythrocyte Maturation Skin Development Positive Regulation Of Erythrocyte Differentiation Spleen Development Cellular Response To Estradiol Stimulus Reactive Oxygen Species Metabolic Process	Monoatomic Ion Transport Monoatomic Ion Transmembrane Transport Proton Transmembrane Transport
Pathways
Drugs
Diseases
GWAS			Iron status biomarkers (ferritin levels) ( 33536631)
Interacting Genes		66 interacting genes: ADGRE2 APOL2 ATP6V0B ATP6V0C BCL2L13 BET1 C1GALT1 C5orf46 CCDC167 CD300C CLDND2 CNIH3 CYB5B CYB5R3 CYP4F2 EMP3 FIS1 FXYD6-FXYD2 GIMAP5 HEXB HMOX1 HMOX2 IER3IP1 IFITM3 INSIG2 LNPEP LPAR3 MFF MS4A13 NINJ2 NKG7 ORMDL2 OTOP3 PLP2 PLPP6 RPRM RTP2 SERP1 SERP2 SLC16A13 SLC30A8 SLC35B4 SLC35G1 SMCO4 SMIM1 STATH STX6 STX7 SYNJ2BP TF TFRC TIMM23 TIMMDC1 TMEM107 TMEM11 TMEM140 TMEM187 TMEM19 TMIE UBE2J1 VAMP1 VAMP3 VAMP4 VKORC1 YIF1A ZDHHC21	8 interacting genes: COMT EBP FAM210B SLC10A1 SLC13A4 TMEM237 TMEM31 ZFYVE27
Entrez ID		116151	347741
HPRD ID		12737	09700
Ensembl ID		ENSG00000124098	ENSG00000182938
Uniprot IDs		Q96KR6	Q7RTS5
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane SNARE Complex SNAP Receptor Activity Golgi Membrane Establishment Of Protein Localization Endoplasmic Reticulum Mitochondrial Outer Membrane Heme Oxidation Heme Oxygenase (decyclizing) Activity SNARE Complex Assembly Organelle Fusion Protein Binding Intracellular Chemical Homeostasis Nitric-oxide Synthase Complex Vesicle Fusion Synaptic Vesicle To Endosome Fusion Transport Vesicle Organelle Membrane Fusion Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Chemical Homeostasis Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Intracellular Monoatomic Cation Homeostasis Nitrite Reductase (NO-forming) Activity Multicellular Organismal-level Iron Ion Homeostasis Clathrin-coated Endocytic Vesicle Membrane Protein Targeting Multicellular Organismal-level Chemical Homeostasis Cellular Homeostasis Intracellular Monoatomic Ion Homeostasis Recycling Endosome Protein Targeting To Mitochondrion Nitric Oxide Metabolic Process Plasma Membrane Reactive Nitrogen Species Metabolic Process Membrane Fusion Cholesterol Biosynthetic Process HFE-transferrin Receptor Complex Negative Regulation Of Fatty Acid Transport Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain Proton-transporting V-type ATPase, V0 Domain Sterol Biosynthetic Process Bleb Assembly Heme Catabolic Process Response To Type II Interferon Golgi Vesicle Transport Azurophil Granule Protein Transport	Cellular Response To Phosphate Starvation Norepinephrine Secretion Catechol O-methyltransferase Activity Membrane Symporter Activity C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Cholestenol Delta-isomerase Activity Sodium:sulfate Symporter Activity Habituation Mastication Renal Sodium Excretion Renal Albumin Absorption Renin Secretion Into Blood Stream Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Steroid Delta-isomerase Activity O-methyltransferase Activity Dopamine Secretion Renal Protein Absorption Catecholamine Catabolic Process Norepinephrine Transport Nonassociative Learning Response To Dopamine Dopamine Catabolic Process Organic Hydroxy Compound Transport Catecholamine Secretion Cerebellar Cortex Morphogenesis Bile Acid Transmembrane Transporter Activity Bile Acid:sodium Symporter Activity Sodium Ion Transport Ossification Involved In Bone Maturation Cone Photoreceptor Outer Segment Rod Photoreceptor Outer Segment Endoplasmic Reticulum Tubular Network Formation Growth Cone Membrane Renal Tubular Secretion Cellular Response To Cocaine
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