FAM210B and SYNJ2BP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM210B	SYNJ2BP
Description		family with sequence similarity 210 member B	synaptojanin 2 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Membrane	Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Inflammatory Response Cell Differentiation Erythrocyte Differentiation Erythrocyte Maturation Skin Development Positive Regulation Of Erythrocyte Differentiation Spleen Development Cellular Response To Estradiol Stimulus Reactive Oxygen Species Metabolic Process	Negative Regulation Of Endothelial Cell Proliferation Protein Targeting Rho Protein Signal Transduction Regulation Of Notch Signaling Pathway Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Regulation Of Endocytosis Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS			Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Motor coordination ( 34177493) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		66 interacting genes: ADGRE2 APOL2 ATP6V0B ATP6V0C BCL2L13 BET1 C1GALT1 C5orf46 CCDC167 CD300C CLDND2 CNIH3 CYB5B CYB5R3 CYP4F2 EMP3 FIS1 FXYD6-FXYD2 GIMAP5 HEXB HMOX1 HMOX2 IER3IP1 IFITM3 INSIG2 LNPEP LPAR3 MFF MS4A13 NINJ2 NKG7 ORMDL2 OTOP3 PLP2 PLPP6 RPRM RTP2 SERP1 SERP2 SLC16A13 SLC30A8 SLC35B4 SLC35G1 SMCO4 SMIM1 STATH STX6 STX7 SYNJ2BP TF TFRC TIMM23 TIMMDC1 TMEM107 TMEM11 TMEM140 TMEM187 TMEM19 TMIE UBE2J1 VAMP1 VAMP3 VAMP4 VKORC1 YIF1A ZDHHC21	34 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1 VANGL2
Entrez ID		116151	55333
HPRD ID		12737	15455
Ensembl ID		ENSG00000124098	ENSG00000213463
Uniprot IDs		Q96KR6	P57105
PDB IDs			2ENO 2JIK 2JIN 7P73 7P74 7PC9 7R2M 7R2T 8AEL
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane SNARE Complex SNAP Receptor Activity Golgi Membrane Establishment Of Protein Localization Endoplasmic Reticulum Mitochondrial Outer Membrane Heme Oxidation Heme Oxygenase (decyclizing) Activity SNARE Complex Assembly Organelle Fusion Protein Binding Intracellular Chemical Homeostasis Nitric-oxide Synthase Complex Vesicle Fusion Synaptic Vesicle To Endosome Fusion Transport Vesicle Organelle Membrane Fusion Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Chemical Homeostasis Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Intracellular Monoatomic Cation Homeostasis Nitrite Reductase (NO-forming) Activity Multicellular Organismal-level Iron Ion Homeostasis Clathrin-coated Endocytic Vesicle Membrane Protein Targeting Multicellular Organismal-level Chemical Homeostasis Cellular Homeostasis Intracellular Monoatomic Ion Homeostasis Recycling Endosome Protein Targeting To Mitochondrion Nitric Oxide Metabolic Process Plasma Membrane Reactive Nitrogen Species Metabolic Process Membrane Fusion Cholesterol Biosynthetic Process HFE-transferrin Receptor Complex Negative Regulation Of Fatty Acid Transport Golgi Lumen Acidification Vacuolar Proton-transporting V-type ATPase, V0 Domain Proton-transporting V-type ATPase, V0 Domain Sterol Biosynthetic Process Bleb Assembly Heme Catabolic Process Response To Type II Interferon Golgi Vesicle Transport Azurophil Granule Protein Transport	Membrane Receptor Complex Low-density Lipoprotein Particle Receptor Activity Apolipoprotein Binding Activin Receptor Activity, Type II Activin Receptor Activity Endocytosis Import Into Cell Astrocyte Activation Involved In Immune Response Cargo Receptor Activity Long-chain Fatty-acyl-CoA Metabolic Process Positive Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Activin Receptor Signaling Pathway Activin Receptor Complex Positive Regulation Of Protein Catabolic Process In The Vacuole Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongation, Saturated Fatty Acid Protein Binding Activin Binding Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Developmental Process Cellular Response To Growth Factor Stimulus Transmembrane Receptor Protein Serine/threonine Kinase Activity Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Apical Protein Localization Response To Growth Factor Clathrin-coated Pit Vesicle-mediated Transport Plasma Membrane Protein Complex Receptor-mediated Endocytosis Retinoid Metabolic Process Regulation Of Developmental Process Gastrulation With Mouth Forming Second Heparan Sulfate Proteoglycan Binding Astrocyte Activation Transport Across Blood-brain Barrier Diterpenoid Metabolic Process Fatty Acid Derivative Metabolic Process Endoplasmic Reticulum Transcytosis Long-chain Fatty-acyl-CoA Biosynthetic Process Regulation Of Amyloid-beta Clearance Regulation Of Cell Differentiation Acyl-CoA Metabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress
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