STAMBPL1 and GNPTAB

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		STAMBPL1	GNPTAB
Description		STAM binding protein like 1	N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
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GO Annotations	Cellular Component	Endosome Cytosol Membrane	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding K63-linked Deubiquitinase Activity Metal-dependent Deubiquitinase Activity	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Calcium Ion Binding Protein Binding Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Metal Ion Binding
	Biological Process	Proteolysis Protein Deubiquitination Cellular Response To Nutrient Levels Protein K63-linked Deubiquitination Cellular Response To L-leucine Protein K6-linked Ubiquitination Negative Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation	Lysosome Organization Protein Secretion Protein Transport N-glycan Processing To Lysosome Secretion Of Lysosomal Enzymes Carbohydrate Phosphorylation Establishment Of Localization In Cell
Pathways		Metalloprotease DUBs
Drugs
Diseases			Mucolipidosis II and III, including: Mucolipidosis II / I-cell disease; Mucolipidosis III A / Pseudo-Hurler polydystrophy; Mucolipidosis III C
GWAS			Bone mineral density (total hip) ( 29883787) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		38 interacting genes: A2M BIRC5 CALCOCO2 CDC37 CEP72 COPS5 COPS6 DUSP1 ECSIT ENOX2 GCSAML GNPTAB GOLGA2 GOLGA6L9 IKZF3 INCA1 LAX1 LCOR MAGEA6 MAST1 MORN5 PLEKHF2 PNMA1 PSEN1 RAB2A RAB2B REL RNF32 SESN2 SF3B5 SMAD2 SMAD7 TCF4 TRIM27 TRIP13 UBC ZNF835 ZRANB1	10 interacting genes: AEN APP DISC1 DSCAM DSCR9 FAM90A1 MAPK1 PSMA1 STAMBPL1 ZNF250
Entrez ID		57559	79158
HPRD ID		16486	11350
Ensembl ID		ENSG00000138134	ENSG00000111670
Uniprot IDs		Q96FJ0	Q3T906
PDB IDs		2ZNR 2ZNV 7L97	2N6D 7S05 7S06 9BGF 9BGG
Enriched GO Terms of Interacting Partners?			Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Axon Positive Regulation Of Phosphate Metabolic Process Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Monoatomic Cation Homeostasis Trans-synaptic Signaling Chemical Synaptic Transmission Positive Regulation Of Mononuclear Cell Migration Regulation Of Response To Calcium Ion Regulation Of Developmental Growth Regulation Of Chemotaxis Cell Body Positive Regulation Of Chemotaxis Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Leukocyte Chemotaxis Neuron Recognition Regulation Of Inflammatory Response Lipoprotein Particle Synaptic Signaling Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Intracellular Monoatomic Ion Homeostasis Microglia Development Glial Cell Development Positive Regulation Of G Protein-coupled Receptor Internalization Synapse Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Regulation Of Axon Extension Positive Regulation Of Axon Extension Positive Regulation Of Axonogenesis Cellular Response To Amino Acid Starvation Cytosine Metabolic Process Interleukin-34-mediated Signaling Pathway Response To Amino Acid Starvation Pyramidal Neuron Migration To Cerebral Cortex Central Region Of Growth Cone DNA Exonuclease Activity Positive Regulation Of Cellular Component Organization Monoatomic Ion Homeostasis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
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