GMIP and GEM

Number of citations of the paper that reports this interaction (PMID 12093360)
11

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		GMIP	GEM
Gene Name		GEM interacting protein	GTP binding protein overexpressed in skeletal muscle
Image
Gene Ontology Annotations	Cellular Component	Intracellular Cytosol	Nucleus Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle
	Molecular Function	Rho GTPase Activator Activity Protein Binding Metal Ion Binding	Magnesium Ion Binding GTPase Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Small GTPase Mediated Signal Transduction Positive Regulation Of Rho GTPase Activity Negative Regulation Of Rho GTPase Activity Intracellular Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction	Immune Response Mitotic Nuclear Division Signal Transduction Cell Surface Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Chromosome Organization Metaphase Plate Congression
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: GEM RHOA	40 interactors: A2M AHCYL1 APOH BLZF1 BMP1 CCDC102B CCDC67 CLDN15 CLEC4G COG8 CTSL GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NL PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB
Entrez ID		51291	2669
HPRD ID		11005	11553
Ensembl ID		ENSG00000089639	ENSG00000164949
Uniprot IDs		B7ZLZ0 E7ERB7 Q9P107	P55040
PDB IDs		3QWE	2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Division Skeletal Muscle Satellite Cell Migration Apolipoprotein A-I-mediated Signaling Pathway Cleavage Furrow Formation Small GTPase Mediated Signal Transduction Mitotic Cell Cycle Process Mitotic Cell Cycle Ossification Involved In Bone Maturation Bone Maturation Negative Chemotaxis Mitotic Spindle Assembly Positive Regulation Of NF-kappaB Import Into Nucleus Cell Cycle Process Regulation Of Osteoblast Proliferation Metaphase Plate Congression Substantia Nigra Development Wound Healing, Spreading Of Cells Positive Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Cytokinesis Cell Cycle Regulation Of NF-kappaB Import Into Nucleus Mitotic Spindle Organization Establishment Of Chromosome Localization Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly Trabecula Morphogenesis Neural Nucleus Development Regulation Of Cytokinesis Rho Protein Signal Transduction Morphogenesis Of An Epithelial Sheet Negative Regulation Of Axonogenesis Regulation Of Stress Fiber Assembly Apical Junction Assembly Intracellular Signal Transduction Positive Regulation Of Axonogenesis Spindle Assembly Midbrain Development Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Ephrin Receptor Signaling Pathway Negative Regulation Of Cell Morphogenesis Involved In Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Cytokinesis Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Cell-cell Junction Assembly Negative Regulation Of Neuron Projection Development Spindle Organization Positive Regulation Of Cell Division Phosphatidylinositol-mediated Signaling	Cellular Component Assembly Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Respiratory Chain Complex I Biogenesis Blood Coagulation, Intrinsic Pathway Extracellular Matrix Disassembly Protein Complex Assembly Mitochondrial Respiratory Chain Complex Assembly Regulation Of Complement Activation Intracellular Transport Regulation Of Protein Binding Spliceosomal Complex Disassembly Establishment Of Localization In Cell Small GTPase Mediated Signal Transduction Extracellular Matrix Organization Extracellular Structure Organization
Tagcloud ?		barr bglf2 bmrf1 borf2 capsid capsids colorimetrically cytomegalovirus ebv epstein fucci g1 gem herpes herpesvirus herpesviruses incoming interfering lytic minority nek9 nima p21 replicates simplex tegument uncharacterized virion virions	annotation centralized clinvar coherent compilation consortium curates curation das elect empowering exome expandable freestanding gbrowse guid https informs interrogation lsdb mseqdr mtdna phenotyping prioritize secure shareholders suite tracks void
Tagcloud (Difference) ?		barr bglf2 bmrf1 borf2 capsid capsids colorimetrically cytomegalovirus ebv epstein fucci g1 herpes herpesvirus herpesviruses incoming interfering lytic minority nek9 nima p21 replicates simplex tegument uncharacterized virion virions	annotation centralized clinvar coherent compilation consortium curates curation das elect empowering exome expandable freestanding gbrowse guid https informs interrogation lsdb mseqdr mtdna phenotyping prioritize secure shareholders suite tracks void
Tagcloud (Intersection) ?		gem